Product Name：P110
CAS No.：2770267-63-3
Synonyms：功能性細(xì)胞穿膜肽P110
Catalog No.：217P626
Brand：Typeptide Biotech（肽研生物）
Description：P110是一種帶有穿透細(xì)胞膜的功能性多肽，序列中含有20個(gè)氨基酸，穩(wěn)定性較好。Drp1 peptide inhibitor P110 (Compound P110) 是選擇性的 Drp1 肽抑制劑，具有神經(jīng)保護(hù)作用。Drp1 peptide inhibitor P110 可抑制 Drp1 的激活，阻止 MPTP 誘導(dǎo)的 Drp1 線(xiàn)粒體轉(zhuǎn)移，并減輕 MPTP 導(dǎo)致的多巴胺能神經(jīng)元丟失、多巴胺能神經(jīng)末梢損傷和行為缺陷，可以用于阿爾茲海默癥的研究。Drp1 peptide inhibitor P110 還可減輕亨廷頓病、腦缺血損傷和心肌梗死動(dòng)物模型中的線(xiàn)粒體損傷和器官損傷。
P110 is a functional peptide with the ability to penetrate cell membranes, containing 20 amino acids in its sequence and exhibiting good stability. P110 is a selective Drp1 peptide inhibitor with neuroprotective effects. Drp1 peptide inhibitor P110 can inhibit the activation of Drp1, prevent MPTP induced mitochondrial transfer of Drp1, and alleviate MPTP induced loss of dopaminergic neurons, damage to dopaminergic nerve endings, and behavioral defects. It can be used for research on Alzheimer's disease. Drp1 peptide inhibitor P110 can also alleviate mitochondrial damage and organ damage in animal models of Huntington's disease, cerebral ischemic injury, and myocardial infarction.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | YGRKKRRQRRRGGDLLPRGS-NH2 |
Sequence(3-letter code) | H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2 |
Peptide Structure | 
|
Molecular Formula | C100H179N45O25 |
Molecular Weight | 2411.8 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： P110;功能性細(xì)胞穿膜肽P110;2770267-63-3;多肽合成;多肽;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專(zhuān)業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷(xiāo)售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類(lèi)型和優(yōu)質(zhì)的產(chǎn)品。