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抑制劑描述：

產(chǎn)品名稱：Captopril

產(chǎn)品別名：卡托普利;甲巰丙脯酸

英文別名：SA333

靶點：Angiotensin-converting Enzyme (ACE)

CAS：62571-86-2

純度：>98%

外觀：白色或類白色結(jié)晶性粉末

保存方法：-20°C

描述：

Captopril是一種血管緊張素轉(zhuǎn)換酶（ACE）抑制劑，IC50為6 nM。

溶解性：DMSO ：21.7 mg/mL (100 mM)
Water ：21.7 mg/mL (100 mM)

體外研究：

Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes. An equimolar ratio of the cis and trans states of Captopril (SQ-14534) exists in solution and that the enzyme selects only the trans state of the inhibitor that presents architectural and stereoelectronic complementarity with its substrate binding groove.

體內(nèi)研究：

產(chǎn)品信息訂購：

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