[Chemical name] (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid, 3-ethyl ester, monohydrochloride [Molecular Formula] C24H28N2O5?HCl [Molecular Weight] 460.96 [CAS Number] 86541-74-4 [Description] White or off white crystalline powder [Quality Standard] CP:YBH00812008 ; USP 32 [Packing] 20KG/Drum [Function and Indication] 1. It’s an ACE inhibitor used for treating moderate hypertension 2. Advantages: 1) Definite curative effect; minimal side effect, clinically treat hypertensive and congestive heart failure 2) WHO recommended as first line anti-hypertension medicine 3) Reduce ventricular afterload without increasing heart rate, improve the status of left ventricular hypertrophy and the glucose tolerance of diabetics 4) Long inhibitory activity time of ACE, quick absorption rate after oral administration and no cumulative effect after repeated doses 2. Mechanism of Action: Upon cleavage of its ester group by the liver after oral administration, benazepril is converted into its active form benazeprilat, which later competitively combines with angiotensin-converting enzyme (ACE) to reduce the activity of angiotensin-converting enzyme (ACE) and to inhibit angiotensin I from converting to angiotensin II by angiotensin-converting enzyme (ACE). In this way, Benazepril Hydrochloridec reduces blood vessel resistance to achieve the goal of lowering blood pressure