一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> The Journal of Organic Chemistry >>article
The Journal of Organic Chemistry

The Journal of Organic Chemistry

IF: 3.3
Download PDF

TEMPO-Mediated Dehydrogenative Hydroxyfluoroalkylation of Arylamines with Polyfluorinated Alcohols

Published:23 April 2024 DOI: 10.1021/acs.joc.4c00185
Xiaoyang Gao, Juting Liao, Hengyi Wei, Ye Xu, Ruirui Zhai, Dulin Kong*, Shuojin Wang* and Xun Chen*, 

Abstract

An efficient 2,2,6,6-tetramethylpiperidinooxy (TEMPO)-mediated hydroxyfluoroalkylation of arylamines with polyfluorinated alcohols via a radical-triggered C(sp2)–H/C(sp3)–H dehydrogenative cross-coupling process was developed. This transformation features simple operation, high atom economy, broad substrate compatibility, and excellent regioselectivity, leading to a series of hydroxyfluoroalkylated arylamine derivatives. Importantly, these synthetic products were further used to evaluate the antitumor activity in cancer cell lines by Cell Counting Kit-8 assay and the outcomes indicated that some compounds show a potent antiproliferative effect.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
TEMPO 2564-83-2 C9H18NO* 671 suppliers $6.00-$2950.00
ARYLAMINES - Inquiry
Polyfluorinated alkyl thiol - Inquiry

Similar articles

IF:3.3

Oxidation of Primary Alcohols and Aldehydes to Carboxylic Acids with 1-Hydroxycyclohexyl Phenyl Ketone

The Journal of Organic Chemistry Yi Lu, Wen-Yun Tan,etc Published: 22 June 2023
IF:4.2

Dess-Martin Periodinane-Mediated Oxidative Coupling Reaction of Isoquinoline with Benzyl Bromide.

Molecules Chunmei Yang, Guoqing Zhang,etc Published: 17 January 2023
仙居县| 广灵县| 永靖县| 株洲市| 桂平市| 绍兴市| 兴仁县| 宜兴市| 吐鲁番市| 长岭县| 伊宁市| 永顺县| 平顶山市| 玉龙| 仙居县| 县级市| 沛县| 红安县| 贞丰县| 大安市| 甘南县| 扶余县| 菏泽市| 瑞昌市| 通城县| 南康市| 沁源县| 阜城县| 阿勒泰市| 苏州市| 荃湾区| 于田县| 乌什县| 江达县| 苍山县| 新巴尔虎右旗| 宁南县| 泰顺县| 巴彦淖尔市| 栾川县| 两当县|