一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> The Journal of Organic Chemistry >>article
The Journal of Organic Chemistry

The Journal of Organic Chemistry

IF: 3.3
Download PDF

TEMPO-Mediated Dehydrogenative Hydroxyfluoroalkylation of Arylamines with Polyfluorinated Alcohols

Published:23 April 2024 DOI: 10.1021/acs.joc.4c00185
Xiaoyang Gao, Juting Liao, Hengyi Wei, Ye Xu, Ruirui Zhai, Dulin Kong*, Shuojin Wang* and Xun Chen*, 

Abstract

An efficient 2,2,6,6-tetramethylpiperidinooxy (TEMPO)-mediated hydroxyfluoroalkylation of arylamines with polyfluorinated alcohols via a radical-triggered C(sp2)–H/C(sp3)–H dehydrogenative cross-coupling process was developed. This transformation features simple operation, high atom economy, broad substrate compatibility, and excellent regioselectivity, leading to a series of hydroxyfluoroalkylated arylamine derivatives. Importantly, these synthetic products were further used to evaluate the antitumor activity in cancer cell lines by Cell Counting Kit-8 assay and the outcomes indicated that some compounds show a potent antiproliferative effect.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
TEMPO 2564-83-2 C9H18NO* 671 suppliers $6.00-$2950.00
ARYLAMINES - Inquiry
Polyfluorinated alkyl thiol - Inquiry

Similar articles

IF:3.3

Oxidation of Primary Alcohols and Aldehydes to Carboxylic Acids with 1-Hydroxycyclohexyl Phenyl Ketone

The Journal of Organic Chemistry Yi Lu, Wen-Yun Tan,etc Published: 22 June 2023
IF:4.2

Dess-Martin Periodinane-Mediated Oxidative Coupling Reaction of Isoquinoline with Benzyl Bromide.

Molecules Chunmei Yang, Guoqing Zhang,etc Published: 17 January 2023
合作市| 中阳县| 德安县| 江永县| 盐边县| 河西区| 车致| 遂昌县| 县级市| 广丰县| 沙湾县| 永安市| 德江县| 叶城县| 盱眙县| 汝城县| 博乐市| 大理市| 眉山市| 年辖:市辖区| 闽清县| 当阳市| 县级市| 霍山县| 乌拉特后旗| 荣成市| 泗阳县| 美姑县| 巴林右旗| 新巴尔虎右旗| 漳浦县| 康平县| 商河县| 嘉善县| 固阳县| 永康市| 万盛区| 灵台县| 陆河县| 洛隆县| 天津市|