一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Environmental Toxicology >>article
Environmental Toxicology

Environmental Toxicology

IF: 4.4
Download PDF

3‐Chloro‐1, 2‐Propanediol Exposure Induces Cardiotoxicity and Behavioural Abnormalities in Zebrafish Embryos

Published:8 December 2024 DOI: 10.1002/tox.24440 PMID: 39648561
Jing Wang,?Qiang Yuan,?Weitao Hu,?Zhijun Ye,?Li Zhang,?Zhipeng Wang,?Jiejun Liu,?Ling Huang,?Fasheng Liu,?Xinjun Liao,?Juhua Xiao,?Shouhua Zhang,?Zigang Cao

Abstract

Numerous contemporary diseases are linked to food contamination. Pathogenic agents might stem from certain food ingredients or result from pollution stemming from food processing or packaging. One such contaminant is 3-Chloro-1,2-propanediol (3-MCPD), it has been previously reported to be produced during the preparation of chemical sauces, as well as during the heating of baked goods. Yet, uncertainty surrounds its potential to induce embryonic developmental toxicity. In this study, zebrafish were employed as the focal point to assess the impact of 3-MCPD on initial embryonic development, heart functionality, and behavior. The research unveiled that exposure of zebrafish embryos to 18, 36, and 54?mM 3-MCPD led to cardiac anomalies, including pericardial edema, reduced heart rate, and elongated SV-BA distance. Additionally, 3-MCPD exposure triggered aberrations in cardiac-related gene expression and an elevation in oxidative stress. Notably, behavioral changes were observed in 3-MCPD-exposed zebrafish embryos, while vascular development appeared unaffected. This study introduces a novel basis for comprehensive exploration of 3-MCPD toxicity.

Substances (1)

Materials
Procduct Name CAS Molecular Formula Supplier Price
Superoxide dismutase 9054-89-1 NULL 471 suppliers $61.90-$3720.00

Similar articles

IF:4.9

Diflubenzuron Induces Cardiotoxicity in Zebrafish Embryos.

International Journal of Molecular Sciences Xue Han,?Xiaowen Xu,etc Published: 8 October 2022
南开区| 前郭尔| 深圳市| 高密市| 师宗县| 屏山县| 岚皋县| 修文县| 乐平市| 常熟市| 绍兴市| 海晏县| 历史| 托里县| 永靖县| 荆州市| 海安县| 北京市| 望城县| 葫芦岛市| 运城市| 兴业县| 德令哈市| 华池县| 泰安市| 仪陇县| 岫岩| 五台县| 芜湖市| 凤台县| 万载县| 阿合奇县| 穆棱市| 浏阳市| 陵水| 石河子市| 井陉县| 永寿县| 灵武市| 仁寿县| 即墨市|