一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> ACS Applied Materials & Interfaces >>article
ACS Applied Materials & Interfaces

ACS Applied Materials & Interfaces

IF: 8.3
Download PDF

Chinese Yam-Derived Adhesive Microgel for Effective Management of Uncontrolled Hemorrhage and Trauma-Induced Skin Wounds

Published:13 December 2024 DOI: 10.1021/acsami.4c16493
Guoqing Zhang, Yangbo Zhou, Yang Feng, Sipin Zhu, Pan Zhuge, Shixuan Chen, Yongjin Fang, Wenbing Wan

Abstract

Chinese yam (Dioscorea opposita), a traditional medicinal plant, has gained renewed interest in contemporary research due to its broad therapeutic potential. In this study, we developed an adhesive yam microgel through a series of peeling, grinding, sieving, and rehydration processes. Our in vitro experiments demonstrated that the yam microgel was noncytotoxic, effectively scavenged free radicals, and promoted cell migration. Additionally, the microgels exhibit good blood compatibility and biodegradability. In vivo, we first evaluated the hemostatic properties of the yam microgel in different hemorrhage models in rats. It demonstrated strong hemostatic capabilities because it could adsorb many blood cells and platelets, activate platelets, and facilitate coagulation. Furthermore, we observed that the yam microgel promotes the repair of acute skin tissue defects by enhancing cell proliferation and neovascularization as well as modulating the inflammatory response, thereby accelerating wound healing. Finally, we found that the yam microgel can serve as a biological adhesive, effectively promoting wound closure through a mechanism similar to its role in facilitating skin tissue repair. The design of a low-cost, safe, and effective yam microgel will provide a promising strategy for hemostasis and wound healing.

Substances (5)

Materials
Procduct Name CAS Molecular Formula Supplier Price
Calcium chloride 10043-52-4 CaCl2 1214 suppliers $5.00-$26371.00
Ethanol 64-17-5 C2H6O 955 suppliers $10.00-$28350.00
Sodium citrate 68-04-2 C6H9NaO7 833 suppliers $6.00-$1110.00
Paraformaldehyde 30525-89-4 (CH2O)x 769 suppliers $17.00-$1190.00
Glutaraldehyde 111-30-8 C5H8O2 621 suppliers $13.50-$2110.00

Similar articles

IF:5.3

Elastic liposomes for skin delivery of dipotassium glycyrrhizinate

International Journal of Pharmaceutics M Trotta, E Peira,etc Published: 25 July 2002
IF:2.8

Evaluation of Bioequivalence and Pharmacokinetic Profiles for Topical Desonide Cream Using Chinese Skins.

Skin Pharmacology and Physiology Yuanyuan Sun,?Nan Yang,etc Published: 19 August 2024
IF:5.4

Usage of Synthetic Peptides in Cosmetics for Sensitive Skin.

ACS Applied Energy Materials Diana I S P Resende, Marta Salvador Ferreira,etc Published: 21 July 2021
罗城| 钟祥市| 普洱| 北安市| 潮安县| 全椒县| 中方县| 西平县| 杭锦后旗| 蓬溪县| 洪湖市| 海安县| 哈巴河县| 雷波县| 阿鲁科尔沁旗| 集贤县| 高台县| 周至县| 奉化市| 泸州市| 精河县| 庄河市| 察雅县| 海原县| 香河县| 温州市| 金寨县| 湖北省| 任丘市| 北宁市| 句容市| 天台县| 丹阳市| 克山县| 灵石县| 肃北| 扎兰屯市| 河曲县| 天全县| 沅江市| 锡林郭勒盟|