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European Journal of Dermatology

European Journal of Dermatology

IF: 2
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Fusidic acid in dermatology: an updated review.

Published:1 January 2010 DOI: 10.1684/ejd.2010.0833 PMID: 20007058
Helmut Sch?fer, Lene Simonsen

Abstract

Studies on the clinical efficacy of fusidic acid in skin and soft-tissue infections (SSTIs), notably those due to Staphylococcus aureus, are reviewed. Oral fusidic acid (tablets dosed at 250 mg twice daily, or a suspension for paediatric use at 20 mg/kg/day given as two daily doses) has shown good efficacy and tolerability. Similarly, plain fusidic acid cream or ointment used two or three times daily in SSTIs such as impetigo are clinically and bacteriologically effective, with minimal adverse events. Combination formulations of fusidic acid with 1% hydrocortisone or 0.1% betamethasone achieve excellent results in infected eczema by addressing both inflammation and infection. A new lipid-rich combination formulation provides an extra moisturizing effect. Development of resistance to fusidic acid has remained generally low or short-lived and can be minimized by restricting therapy to no more than 14 days at a time.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Hydrocortisone 50-23-7 C21H30O5 945 suppliers $25.00-$15100.00
Betamethasone 378-44-9 C22H29FO5 722 suppliers $39.00-$1504.50
Fusidic Acid 6990-06-3 C31H48O6 402 suppliers $5.00-$2333.10

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