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Biomedicine & Pharmacotherapy

Biomedicine & Pharmacotherapy

IF: 6.9
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Pharmacological effects and mechanisms of tannic acid

Published:1 October 2022 DOI: 10.1016/j.biopha.2022.113561 PMID: 36029537
Wang Jing , Chen Xiaolan , Chen Yu , Qin Feng , Yang Haifeng

Abstract

In recent years, increasing attention has been paid to the pharmacological efficacy of tannins. Tannic acid (TA), the simplest hydrolysable tannin that has been approved by the FDA as a safe food additive, is one of the most important components of these traditional medicines. Studies have shown that TA displays a wide range of pharmacological activities, such as anti-inflammatory, neuroprotective, antitumor, cardioprotective, and anti-pathogenic effects. Here, we summarize the known pharmacological effects and associated mechanisms of TA. We focus on the effect and mechanism of TA in various animal models of inflammatory disease and organ, brain, and cardiovascular injury. Moreover, we discuss the possible molecular targets and signaling pathways of TA, in addition to the pharmacological effects of TA-based nanoparticles and TA in combination with chemotherapeutic drugs.

Substances (2)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Tannic acid 1401-55-4 C76H52O46 911 suppliers $10.00-$4499.30
1-Triacontanol 593-50-0 C30H62O 475 suppliers $20.00-$1311.00

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