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Molecular Microbiology

Molecular Microbiology

IF: 2.6
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The phenylacetyl‐CoA catabolon: a complex catabolic unit with broad biotechnological applications

Published:1 March 2001 DOI: 10.1046/j.1365-2958.2001.02344.x
J. Luengo,?José L. García,?E. R. Olivera

Abstract

The term catabolon was introduced to define a complex functional unit integrated by different catabolic pathways, which are, or could be, co‐ordinately regulated, and that catalyses the transformation of structurally related compounds into a common catabolite. The phenylacetyl‐CoA catabolon encompasses all the routes involved in the transformation of styrene, 2‐phenylethylamine, trans‐styrylacetic acid, phenylacetaldehyde, phenylacetic acid, phenylacetyl amides, phenylacetyl esters and n‐phenylalkanoic acids containing an even number of carbon atoms, into phenylacetyl‐CoA. This common intermediate is subsequently catabolized through a route of convergence, the phenylacetyl‐CoA catabolon core, into general metabolites. The genetic organization of this central route, the biochemical significance of the whole functional unit and its broad biotechnological applications are discussed.

Substances (7)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Styrene 100-42-5 C8H8 738 suppliers $7.62-$2055.90
Phenylacetaldehyde 122-78-1 C8H8O 390 suppliers $10.00-$1456.00
trans-Styrylacetic acid 1914-58-5 C10H10O2 91 suppliers $10.00-$1415.42
TRANS-STYRYLACETIC ACID 2243-53-0 C10H10O2 24 suppliers Inquiry
Phenylacetyl-CoA 7532-39-0 C29H42N7O17P3S 16 suppliers $154.00-$2100.00
GINKGOLIC ACIDS 13 suppliers Inquiry
Phenylacetyl-Coenzyme A (sodium salt) 5 suppliers Inquiry

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