一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Journal of Nanobiotechnology >>article
Journal of Nanobiotechnology

Journal of Nanobiotechnology

IF: 10.6
Download PDF

Multifunctional antibacterial bioactive nanoglass hydrogel for normal and MRSA infected wound repair

Published:21 May 2023 DOI: 10.1186/s12951-023-01929-9 PMID: 37211601
Long Zhang, Wen Niu, Yuyao Lin, Junping Ma, Tongtong Leng, Wei Cheng, Yidan Wang, Min Wang, Jingya Ning, Shuanying Yang, Bo Lei

Abstract

Large-scale skin damage brings potential risk to patients, such as imbalance of skin homeostasis, inflammation, fluid loss and bacterial infection. Moreover, multidrug resistant bacteria (MDRB) infection is still a great challenge for skin damage repair. Herein, we developed an injectable self-healing bioactive nanoglass hydrogel (FABA) with robust antibacterial and anti-inflammatory ability for normal and Methicillin-resistant Staphylococcus aureus (MRSA) infected skin wound repair. FABA hydrogel was fabricated facilely by the self-crosslinking of F127-CHO (FA) and alendronate sodium (AL)-decorated Si-Ca-Cu nanoglass (BA). FABA hydrogel could significantly inhibit the growth of Staphylococcus aureus, Escherichia coli and MRSA in vitro, while showing good cytocompatibility and hemocompatibility. In addition, FABA hydrogel could inhibit the expression of proinflammatory factor TNF-α and enhance the expression of anti-inflammatory factor IL-4/ IL-10. Based on its versatility, FABA hydrogel could complete wound closure efficiently (75% at day 3 for normal wound, 70% at day 3 for MRSA wound), which was almost 3 times higher than control wound, which was related with the decrease of inflammatory factor in early wound. This work suggested that FABA hydrogel could be a promising dressing for acute and MRSA-infected wound repair.

Similar articles

IF:10.7

Antibacterial betaine modified chitosan-based hydrogel with angiogenic property for photothermal enhanced diabetic wound repairing

Carbohydrate Polymers Kaiyue Zhang, Jingjing Zhu,etc Published: 19 November 2024
IF:15.5

Glycoengineered extracellular vesicles released from antibacterial hydrogel facilitate diabetic wound healing by promoting angiogenesis

Journal of Extracellular Vesicles Kewei Wang, Qin He,etc Published: 27 November 2024
IF:0

Bioactivity of Mupirocin Nanoparticle-Loaded Hydrogel against Methicillin-Resistant Staphylococcus aureus (MRSA)

Applied microbiology Sukanjana Kamlungmak,?Monwadee Wonglapsuwan,etc Published: 3 March 2022
老河口市| 名山县| 吉木萨尔县| 南靖县| 泗水县| 会东县| 烟台市| 洪湖市| 贵州省| 青田县| 博罗县| 射阳县| 措美县| 昌黎县| 诏安县| 资溪县| 中牟县| 景宁| 长葛市| 密云县| 林周县| 阿克| 洪泽县| 珲春市| 文安县| 靖边县| 浙江省| 通渭县| 湄潭县| 汶川县| 鞍山市| 襄垣县| 太白县| 龙陵县| 襄樊市| 金华市| 水富县| 益阳市| 遂川县| 承德县| 梅州市|