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CNS Neuroscience & Therapeutics
CNS Neuroscience & Therapeutics
IF:4.8
CiteScore:7.3
Articles:240
CNS Neuroscience & Therapeutics provides a medium for rapid publication of original clinical, experimental, and translational research papers, timely reviews and reports of novel findings of therapeutic relevance to the central nervous system, as well as papers related to clinical pharmacology, drug development and novel methodologies for drug evaluation. The journal focuses on neurological and psychiatric diseases such as stroke, Parkinson’s disease, Alzheimer’s disease, depression, schizophrenia, epilepsy, and drug abuse.
The Role of P62/Nrf2/Keap1 Signaling Pathway in Lead-Induced Neurological Dysfunction
Published: 5 September 2025
DOI: 10.1111/cns.70566
Dongjie Peng, Peiqi Wei, Zhenning Li, Ruokun Wei, Huishuai Li, Shaojun Li
Dongjie Peng, Peiqi Wei, Zhenning Li, Ruokun Wei, Huishuai Li, Shaojun Li
mGluR5 in Pyramidal Neurons in the Hippocampus Mediates Chronic Stress-Induced Memory Deficits
Published: 12 June 2025
DOI: 10.1111/cns.70477
Hong-Cheng Lu, Zhuo-Jun Du, Hao Chen, Ting Guo, Shu-Cai Yang, Xin Li
Hong-Cheng Lu, Zhuo-Jun Du, Hao Chen, Ting Guo, Shu-Cai Yang, Xin Li
Xiao-Chai-Hu-Tang Ameliorates Depressive Symptoms via Modulating Neuro-Endocrine Network in Chronic Unpredictable Mild Stress-Induced Mice
Published: 21 February 2025
DOI: 10.1111/cns.70290
Ying Feng, Wenkai Wang, Yingru Zhang, Yuanyuan Feng, Yiyang Zhao, Zhaozhou Zhang, Yan Wang
Ying Feng, Wenkai Wang, Yingru Zhang, Yuanyuan Feng, Yiyang Zhao, Zhaozhou Zhang, Yan Wang
Impaired Basal Forebrain Cholinergic Neuron GDNF Signaling Contributes to Perioperative Sleep Deprivation–Induced Chronicity of Postsurgical Pain in Mice?…
Published: 1 December 2024
DOI: 10.1111/cns.70147
Dong Wang,?Shi-Nan Wei,?Lu Zhang,?Zhi-Chen Lang,?Si-Nian Wang,?Bo Cheng,?Yan Lu,?Xiu Wang,?Wei Wang,?Feng-Sheng Li,?Hao Zhang
Dong Wang,?Shi-Nan Wei,?Lu Zhang,?Zhi-Chen Lang,?Si-Nian Wang,?Bo Cheng,?Yan Lu,?Xiu Wang,?Wei Wang,?Feng-Sheng Li,?Hao Zhang
The Circadian Clock Gene Bmal1 Regulates Microglial Pyroptosis After Spinal Cord Injury via NF‐κB/MMP9
Published: 1 December 2024
DOI: 10.1111/cns.70130
Dachuan Li,?Siyang Liu,?Xiao Lu,?Zhaoyang Gong,?Hongli Wang,?Xinlei Xia,?Feizhou Lu,?Jianyuan Jiang,?Yuxuan Zhang,?Guangyu Xu,?Fei Zou,?Xiaosheng Ma
Dachuan Li,?Siyang Liu,?Xiao Lu,?Zhaoyang Gong,?Hongli Wang,?Xinlei Xia,?Feizhou Lu,?Jianyuan Jiang,?Yuxuan Zhang,?Guangyu Xu,?Fei Zou,?Xiaosheng Ma
CCN1 Promotes Mesenchymal Phenotype Transition Through Activating NF‐κB Signaling Pathway Regulated by S100A8 in Glioma Stem Cells
Published: 1 December 2024
DOI: 10.1111/cns.70128
Xing Guo,?Shuhua Guo,?Feng Tian,?Zijie Gao,?Yang Fan,?Chuanxin Wang,?Shuo Xu
Xing Guo,?Shuhua Guo,?Feng Tian,?Zijie Gao,?Yang Fan,?Chuanxin Wang,?Shuo Xu
9‐Methylfascaplysin Prevents Neuroinflammation and Synaptic Damage via Cell‐Specific Inhibition of Kinases in?APP/PS1 Transgenic Mice
Published: 19 November 2024
DOI: 10.1111/cns.70100
Jingyang Le, Chenglong Xia, Jiayi Xu, Jinhan Cai, Chenwei Hu, Yu Bai, Huiyue Chen, Wenni Rong, Yujie Jiang, Xinming Wu, Yongmei Li, Qiyao Wang, C. Benjamin Naman, Hua Wei, Jili Zhang, Hao Liu, Xiaowei Chen, Fufeng Liu, Hongze Liang, Wei Cui
Jingyang Le, Chenglong Xia, Jiayi Xu, Jinhan Cai, Chenwei Hu, Yu Bai, Huiyue Chen, Wenni Rong, Yujie Jiang, Xinming Wu, Yongmei Li, Qiyao Wang, C. Benjamin Naman, Hua Wei, Jili Zhang, Hao Liu, Xiaowei Chen, Fufeng Liu, Hongze Liang, Wei Cui
Exosome‐transmitted podoplanin promotes tumor‐associated macrophage‐mediated immune tolerance in glioblastoma
Published: 12 March 2024
DOI: 10.1111/cns.14643
Mengwan Wu, Ying Shi, Yuyang Liu, Hongxiang Huang, Jiajia Che, Jing Shi, Chuan Xu
Mengwan Wu, Ying Shi, Yuyang Liu, Hongxiang Huang, Jiajia Che, Jing Shi, Chuan Xu
Carpesii fructus extract exhibits neuroprotective effects in cellular and Caenorhabditis elegans models of Parkinson's disease
Published: 31 October 2023
DOI: 10.1111/cns.14515
Feng-Dan Zhu, Bin-Ding Wang, Da-Lian Qin, Xiao-Hui Su, Lu Yu, Jian-Ming Wu, Betty Yuen-Kwan Law, Min-Song Guo, Chong-Lin Yu, Xiao-Gang Zhou, An-Guo Wu
Feng-Dan Zhu, Bin-Ding Wang, Da-Lian Qin, Xiao-Hui Su, Lu Yu, Jian-Ming Wu, Betty Yuen-Kwan Law, Min-Song Guo, Chong-Lin Yu, Xiao-Gang Zhou, An-Guo Wu
Enriched environment ameliorates fear memory impairments induced by sleep deprivation via inhibiting PIEZO1/calpain/autophagy signaling pathway in the basal forebrain.
Published: 23 July 2023
DOI:
Zi-qing Zhang, Yan Lu, Hao Zhang, Su-he Dong, Ya-tong Wu, Si-nian Wang, Ai-hua Huang, Qi-sheng Jiang, Shi-min Yin
Zi-qing Zhang, Yan Lu, Hao Zhang, Su-he Dong, Ya-tong Wu, Si-nian Wang, Ai-hua Huang, Qi-sheng Jiang, Shi-min Yin
Psilocin suppresses methamphetamine-induced hyperlocomotion and acquisition of conditioned place preference via D2R-mediated ERK signaling
Published: 10 January 2023
DOI: 10.1111/cns.14054
Jing Wang, Min Liang, Qing Shang, Hongyan Qian, Ran An, Hua Liu, Gaojie Shao, Tao Li, Xinshe Liu
Jing Wang, Min Liang, Qing Shang, Hongyan Qian, Ran An, Hua Liu, Gaojie Shao, Tao Li, Xinshe Liu
Quetiapine Fumarate for the Treatment of Multiple Sclerosis: Focus on Myelin Repair
Published: 22 July 2013
DOI: 10.1111/cns.12154
Simon Zhornitsky, Voon Wee Yong, Marcus W. Koch, Aaron Mackie, Stéphane Potvin, Scott B. Patten, Luanne M. Metz
Simon Zhornitsky, Voon Wee Yong, Marcus W. Koch, Aaron Mackie, Stéphane Potvin, Scott B. Patten, Luanne M. Metz