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Nucleic Acids Research

Nucleic Acids Research

IF:16.6 CiteScore:27.1 Articles:1057
Nucleic Acids Research (NAR) is a scientific journal that publishes research on various aspects of nucleic acids and proteins involved in nucleic acid metabolism and interactions. It covers areas such as chemistry and synthetic biology, computational biology, gene regulation, chromatin and epigenetics, genome integrity, repair and replication, genomics, molecular biology, nucleic acid enzymes, RNA, and structural biology. The journal also includes a Survey and Summary section for brief reviews. Additionally, each year, the first issue is dedicated to biological databases, and an issue in July focuses on web-based software resources for the biological community. Nucleic Acids Research is indexed by several services including Abstracts on Hygiene and Communicable Diseases, Animal Breeding Abstracts, Agricultural Engineering Abstracts, Agbiotech News and Information, BIOSIS Previews, CAB Abstracts, and EMBASE.

RNA G-quadruplex structure-based PROTACs for targeted DHX36 protein degradation and gene activity modulation in mammalian cells

Published: 24 January 2025 DOI: 10.1093/nar/gkaf039
Kun Zhang,Qichang Nie,Maolin Li,Xiaona Chen,Liting Zhong,Tianle Dai,Xiaofan Guo,Haizhou Zhao,Terrence Chi-Kong Lau,Huating Wang,Shuo-Bin Chen,Chun Kit Kwok

Programming ADAR-recruiting hairpin RNA sensor to detect endogenous molecules

Published: 14 December 2024 DOI: 10.1093/nar/gkae1146
Pei-Pei Qin, Pin-Ru Chen, Liu Tan, Xiaohe Chu, Bang-Ce Ye, Bin-Cheng Yin

ALKBH5 governs human endoderm fate by regulating the DKK1/4-mediated Wnt/β-catenin activation.

Published: 14 October 2024 DOI: 10.1093/nar/gkae707
Zechuan Liang,?Tao Huang,?Wei Li,?Zhaoyi Ma,?Kaipeng Wang,?Ziwei Zhai,?Yixin Fan,?Yu Fu,?Xiaomin Wang,?Yue Qin,?Bo Wang,?Chengchen Zhao,?Junqi Kuang,?Duanqing Pei

Fluoropyrimidines trigger decay of hypomodified tRNA in yeast.

Published: 10 June 2024 DOI: 10.1093/nar/gkae341
Katharina G?rlitz,?Larissa Bessler,?Mark Helm,?Raffael Schaffrath,?Roland Klassen

Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level

Published: 13 October 2023 DOI: 10.1093/nar/gkad735
Yilun Sun,?Jiji Chen,?Yves Pommier

Dot1l cooperates with Npm1 to repress endogenous retrovirus MERVL in embryonic stem cells

Published: 22 September 2023 DOI: 10.1093/nar/gkad640
Xin Zhao, Xiaomin Li, Haiyang Sun, Xuan Zhao, Tingting Gao, Panpan Shi, Fuquan Chen, Lin Liu, Xinyi Lu

CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference

Published: 21 March 2022 DOI: 10.1093/nar/gkac108
Shuye Tian, Bin Zhang, Yuhao He, Zhiyuan Sun, Jun Li, Yisheng Li, Hongyang Yi, Yan Zhao, Xudong Zou, Yunfei Li, Huanhuan Cui, Liang Fang, Xin Gao, Yuhui Hu, Wei Chen

Small-molecule compounds boost genome-editing efficiency of cytosine base editor

Published: 7 September 2021 DOI: 10.1093/nar/gkab645
Tianyuan Zhao, Qing Li, Chenchen Zhou, Xiujuan Lv, Hongyan Liu, Tianxiang Tu, Na Tang, Yanbo Cheng, Xiaoyu Liu, Changbao Liu, Junzhao Zhao, Zongming Song, Haoyi Wang, Jinsong Li, Feng Gu

Rph1 coordinates transcription of ribosomal protein genes and ribosomal RNAs to control cell growth under nutrient stress conditions

Published: 4 September 2020 DOI: 10.1093/nar/gkaa558
Wen-Jie Shu, Runfa Chen, Zhao-Hong Yin, Feng Li, Heng Zhang, Hai-Ning Du
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