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Pharmacological research

IF:9.1 CiteScore:18.7 Articles:491

Pharmacological Research publishes cutting-edge articles in biomedical sciences to cover a broad range of topics that move the pharmacological field forward. Pharmacological research publishes articles on molecular, biochemical, translational, and clinical research (including clinical trials); it is proud of its rapid publication of accepted papers that comprises a dedicated, fast acceptance and publication track for high profile articles.

Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors.

Published: 1 November 2022 DOI: 10.1016/j.phrs.2022.106487
Geer Chen , Xiaoyu Zhu , Jiaqi Li, Yao Zhang, Xiaoxuan Wang, Ren Zhang, Xinchen Qin, Xi Chen, Junyi Wang, Weilin Liao, Zongjin Wu, Lu Lu, Weiyu Wu, Haijie Yu, Lijuan Ma

Reciprocal positive regulation between BRD4 and YAP in GNAQ-mutant uveal melanoma cells confers sensitivity to BET inhibitors

Published: 1 October 2022 DOI: 10.1016/j.phrs.2022.106464
Gui-Ming Zhang , Si-Si Huang , Lin-Xuan Ye , Xiao-Lian Liu , Wen-Hui Shi , Zhong-Lu Ren , Run-Hua Zhou , Jia-Jie Zhang , Jing-Xuan Pan , Shu-Wen Liu , Le Yu , Yi-Lei Li

Deoxyhypusine hydroxylase as a novel pharmacological target for ischemic stroke via inducing a unique post-translational hypusination modification

Published: 1 February 2022 DOI: 10.1016/j.phrs.2021.106046
Qiang Guo , Yi-Chi Zhang , Wei Wang , Yu-Qi Wang , Yang Liu , Zhuo Yang , Mei-Mei Zhao , Na Feng , Yan-Hang Wang , Xiao-Wen Zhang , Heng Yang , Ting-Ting Liu , Lun-Yong Shi , Xiao-Meng Shi , Dan Liu , Peng-Fei Tu , Ke-Wu Zeng

Unraveling the metabolic pathway of choline-TMA-TMAO: Effects of gypenosides and implications for the therapy of TMAO related diseases

Published: 1 November 2021 DOI: 10.1016/j.phrs.2021.105884
Qiao Zhang , Xiaomin Guo , Cao Xie , Zhonglian Cao , Xin Wang , Li Liu , Ping Yang

Chlorquinaldol targets the β-catenin and T-cell factor 4 complex and exerts anti-colorectal cancer activity.

Published: 1 September 2020 DOI: 10.1016/j.phrs.2020.104955
Ling Wang, Ke Deng, Liang Gong, Liang Zhou, Sapna Sayed, Huan Li, Qi Sun, Zijie Su, Zhongyuan Wang, Shanshan Liu, Huifang Zhu, Jiaxing Song, Desheng Lu

Cardamonin retards progression of autosomal dominant polycystic kidney disease via inhibiting renal cyst growth and interstitial fibrosis.

Published: 1 May 2020 DOI: 10.1016/j.phrs.2020.104751
Jinzhao He , Hong Zhou , Jia Meng , Shun Zhang , Xiaowei Li , Shuyuan Wang , Guangying Shao , William Jin , Xiaoqiang Geng , Shuai Zhu , Baoxue Yang

Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.

Published: 1 September 2019 DOI: 10.1016/j.phrs.2019.104396
Jin-Feng Teng , Da-Lian Qin , Qi-Bing Mei , Wen-Qiao Qiu , Rong Pan , Rui Xiong , Ya Zhao , Betty Yuen-Kwan Law , Vincent Kam-Wai Wong , Yong Tang , Chong-Lin Yu , Feng Zhang , Jian-Ming Wu , An-Guo Wu

Ononin, sec-O-β-d-glucosylhamaudol and astragaloside I: antiviral lead compounds identified via high throughput screening and biological validation from traditional Chinese medicine Zhongjing formulary

Published: 1 July 2019 DOI: 10.1016/j.phrs.2019.04.032
Yunru Yu , Zhenhao Li , Rui Guo , Jing Qian , Han Zhang , Junhua Zhang , Xiaoping Zhao , Shufang Wang , Yi Wang

Skeletal muscle atrophy: Potential therapeutic agents and their mechanisms of action

Published: 1 September 2015 DOI: 10.1016/j.phrs.2015.05.010
Vikas Dutt , Sanjeev Gupta , Rajesh Dabur , Elisha Injeti , Ashwani Mittal

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