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Scientific Reports
Scientific Reports
IF:3.8
CiteScore:7.5
Articles:19567
We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections.
Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021).
?Engineering
Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live.
?Physical sciences
Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.
?Earth and environmental sciences
Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems.
?Biological sciences
Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
?Health sciences
The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
IGSF6 is a novel biomarker to evaluate immune infiltration in mismatch repair-proficient colorectal cancer
Published: 21 November 2023
DOI: 10.1038/s41598-023-47739-9
Yu-Ming Rong,?Yu-Cheng Xu,?Xiao-Chuan Chen,?Min-Er Zhong,?Ying-Xin Tan,?Yu-Fan Liang,?Jing-Rong Weng,?Jun Liu,?Xin-You Wang,?Dan-Dong Luo,?Yi-Ran Bie,?Xi Chen,?Jia-Wei Cai,?Zhao-Liang Yu,?Yi-Feng Zou
Yu-Ming Rong,?Yu-Cheng Xu,?Xiao-Chuan Chen,?Min-Er Zhong,?Ying-Xin Tan,?Yu-Fan Liang,?Jing-Rong Weng,?Jun Liu,?Xin-You Wang,?Dan-Dong Luo,?Yi-Ran Bie,?Xi Chen,?Jia-Wei Cai,?Zhao-Liang Yu,?Yi-Feng Zou
A novel pathway of levodopa metabolism by commensal Bifidobacteria
Published: 6 November 2023
DOI: 10.1038/s41598-023-45953-z
M S Cirstea,?A Creus-Cuadros,?C Lo,?A C Yu,?A Serapio-Palacios,?S Neilson,?S Appel-Cresswell,?B B Finlay
M S Cirstea,?A Creus-Cuadros,?C Lo,?A C Yu,?A Serapio-Palacios,?S Neilson,?S Appel-Cresswell,?B B Finlay
4-Methylumbelliferone enhances the effects of chemotherapy on both temozolomide-sensitive and resistant glioblastoma cells.
Published: 8 June 2023
DOI: 10.1038/s41598-023-35045-3
Matías A Pibuel,?Daniela Poodts,?Sofía A Sias,?Agustín Byrne,?Silvia E Hajos,?Paula G Franco,?Silvina L Lompardía
Matías A Pibuel,?Daniela Poodts,?Sofía A Sias,?Agustín Byrne,?Silvia E Hajos,?Paula G Franco,?Silvina L Lompardía
Single-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis
Published: 26 April 2023
DOI: 10.1038/s41598-023-32093-7
Chen-Qian Zhao, Chong Wang, Meng-Meng Liu, Meng Cao, Jie Peng, De-Qin Kong, Xiao-Ting Ren, Rui Liu, Chun-Xu Hai, Xiao-di Zhang
Chen-Qian Zhao, Chong Wang, Meng-Meng Liu, Meng Cao, Jie Peng, De-Qin Kong, Xiao-Ting Ren, Rui Liu, Chun-Xu Hai, Xiao-di Zhang
Protective effect of urotensin II receptor antagonist urantide and exercise training on doxorubicin-induced cardiotoxicity
Published: 23 January 2023
DOI: 10.1038/s41598-023-28437-y
Jing Sun,?Jiedong Zhou,?Shimin Sun,?Hui Lin,?Hanlin Zhang,?Zuoquan Zhong,?Jufang Chi,?HangYuan Guo
Jing Sun,?Jiedong Zhou,?Shimin Sun,?Hui Lin,?Hanlin Zhang,?Zuoquan Zhong,?Jufang Chi,?HangYuan Guo
Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells
Published: 2 November 2022
DOI: 10.1038/s41598-022-21034-5
Xammy Huu Wrynla,?Eddie Wehri,?Erik Van Dis,?Scott B Biering,?Livia H Yamashiro,?Chi Zhu,?Julien Stroumza,?Claire Dugast-Darzacq,?Thomas G W Graham,?Xuanting Wang,?Steffen Jockusch,?Chuanjuan Tao,?Minchen Chien,?Wei Xie,?Dinshaw J Patel,?Cindy Meyer,?Aitor Garzia,?Thomas Tuschl,?James J Russo,?Jingyue Ju,?Anders M N??r,?Sarah Stanley,?Julia Schaletzky
Xammy Huu Wrynla,?Eddie Wehri,?Erik Van Dis,?Scott B Biering,?Livia H Yamashiro,?Chi Zhu,?Julien Stroumza,?Claire Dugast-Darzacq,?Thomas G W Graham,?Xuanting Wang,?Steffen Jockusch,?Chuanjuan Tao,?Minchen Chien,?Wei Xie,?Dinshaw J Patel,?Cindy Meyer,?Aitor Garzia,?Thomas Tuschl,?James J Russo,?Jingyue Ju,?Anders M N??r,?Sarah Stanley,?Julia Schaletzky
Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel.
Published: 19 September 2022
DOI: 10.1038/s41598-022-19621-7
Riley Plett, Paul Mellor, Stephanie Kendall, S Austin Hammond, Aren Boulet, Kristine Plaza, Frederick S Vizeacoumar, Franco J Vizeacoumar, Deborah H Anderson
Riley Plett, Paul Mellor, Stephanie Kendall, S Austin Hammond, Aren Boulet, Kristine Plaza, Frederick S Vizeacoumar, Franco J Vizeacoumar, Deborah H Anderson
Design, synthesis and biological activities of echinopsine derivatives containing acylhydrazone moiety
Published: 21 February 2022
DOI: 10.1038/s41598-022-06775-7
Peipei Cui, Mingjiang Cai, Yanan Meng, Yan Yang, Hongjian Song, Yuxiu Liu, Qingmin Wang
Peipei Cui, Mingjiang Cai, Yanan Meng, Yan Yang, Hongjian Song, Yuxiu Liu, Qingmin Wang
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide
Published: 30 August 2021
DOI: 10.1038/s41598-021-96647-3
Jing Li, Yuchen Sun, Xuanzi Sun, Xu Zhao, Yuan Ma, Yuzhu Wang, Xiaozhi Zhang
Jing Li, Yuchen Sun, Xuanzi Sun, Xu Zhao, Yuan Ma, Yuzhu Wang, Xiaozhi Zhang
Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin
Published: 28 January 2020
DOI: 10.1038/s41598-020-57843-9
Alexander Herrmann, Manfred Roesner, Thomas Werner, Stefanie M Hauck, Alisha Koch, Amelie Bauer, Martha Schneider, Ruth Brack-Werner
Alexander Herrmann, Manfred Roesner, Thomas Werner, Stefanie M Hauck, Alisha Koch, Amelie Bauer, Martha Schneider, Ruth Brack-Werner
Reversine exhibits antineoplastic activity in JAK2V617F-positive myeloproliferative neoplasms
Published: 9 July 2019
DOI: 10.1038/s41598-019-46163-2
Keli Lima, Jorge Antonio Elias Godoy Carlos, Raquel de Melo Alves-Paiva, Hugo Passos Vicari, Fábio Pires de Souza Santos, Nelson Hamerschlak, Leticia Veras Costa-Lotufo, Fabiola Traina, Jo?o Agostinho Machado-Neto
Keli Lima, Jorge Antonio Elias Godoy Carlos, Raquel de Melo Alves-Paiva, Hugo Passos Vicari, Fábio Pires de Souza Santos, Nelson Hamerschlak, Leticia Veras Costa-Lotufo, Fabiola Traina, Jo?o Agostinho Machado-Neto
Cardol triene inhibits dengue infectivity by targeting kl loops and preventing envelope fusion
Published: 9 November 2018
DOI: 10.1038/s41598-018-35035-w
Parichat Kanyaboon, Thanaphon Saelee, Aphinya Suroengrit, Kowit Hengphasatporn, Thanyada Rungrotmongkol, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn
Parichat Kanyaboon, Thanaphon Saelee, Aphinya Suroengrit, Kowit Hengphasatporn, Thanyada Rungrotmongkol, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn
LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent
Published: 8 October 2018
DOI: 10.1038/s41598-018-33039-0
Hyun-Wook Han, Soojung Hahn, Hye Yun Jeong, Joo-Hyun Jee, Myoung-Ok Nam, Han Kyung Kim, Dong Hyeon Lee, So-Young Lee, Dong Kyu Choi, Ji Hoon Yu, Sang-Hyun Min, Jongman Yoo
Hyun-Wook Han, Soojung Hahn, Hye Yun Jeong, Joo-Hyun Jee, Myoung-Ok Nam, Han Kyung Kim, Dong Hyeon Lee, So-Young Lee, Dong Kyu Choi, Ji Hoon Yu, Sang-Hyun Min, Jongman Yoo
C19, a C-terminal peptide of CKLF1, decreases inflammation and proliferation of dermal capillaries in psoriasis
Published: 24 October 2017
DOI: 10.1038/s41598-017-13799-x
Yi Zheng, Yixuan Wang, Xuan Zhang, Yaqi Tan, Shiguang Peng, Le Chen, Yanling He
Yi Zheng, Yixuan Wang, Xuan Zhang, Yaqi Tan, Shiguang Peng, Le Chen, Yanling He
Halogenated Chrysins Inhibit Dengue and Zika Virus Infectivity
Published: 20 October 2017
DOI: 10.1038/s41598-017-14121-5
Aphinya Suroengrit, Wanchalerm Yuttithamnon, Pimsiri Srivarangkul, Saran Pankaew, Krongkan Kingkaew, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn
Aphinya Suroengrit, Wanchalerm Yuttithamnon, Pimsiri Srivarangkul, Saran Pankaew, Krongkan Kingkaew, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn
CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways
Published: 7 July 2017
DOI: 10.1038/s41598-017-05072-y
In-Yu Lin, Min-Hsiung Pan, Ching-Shu Lai, Ting-Ting Lin, Chiung-Tong Chen, Tao-Sheng Chung, Chien-Lung Chen, Chen-Huan Lin, Wu-Chang Chuang, Ming-Chung Lee, Ching-Che Lin, Nianhan Ma
In-Yu Lin, Min-Hsiung Pan, Ching-Shu Lai, Ting-Ting Lin, Chiung-Tong Chen, Tao-Sheng Chung, Chien-Lung Chen, Chen-Huan Lin, Wu-Chang Chuang, Ming-Chung Lee, Ching-Che Lin, Nianhan Ma