LY-2584702 (tosylate salt)
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- $10 - $3196
- Product name: LY-2584702 (tosylate salt)
- CAS: 1082949-68-5
- MF: C28H27F4N7O3S
- MW: 617.62
- EINECS:
- MDL Number:MFCD29054739
- Synonyms:4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1);LY-2584702 (tosylate salt);LY2584702 Tosylate;4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine p-toluenesulfonate;LY-2584702;LY 2584702;LYS6K2;LYS6K2;LYS6K2(LY2584702) tosylate salt;CS-2145
75 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 25mg
- 50.00mg
- 50mg
- 100mg
- 100.00mg
- 250.00mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5 mg
- 25 mg
- 10mM*1mLinDMSO(Solution)
- 250mg
- 500mg
- 1g
- Manufactureraablocks
- Product numberAA008TJO
- Product description4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99%
- Packaging1mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TJO
- Product description4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99%
- Packaging5mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TJO
- Product description4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99%
- Packaging10mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TJO
- Product description4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99%
- Packaging25mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TJO
- Product description4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate 99%
- Packaging50mg
- Price$46
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TJO
- Product description4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99%
- Packaging100mg
- Price$90
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number3528DG
- Product descriptionLY-2584702(tosylatesalt)
- Packaging50mg
- Price$735
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0229
- Product descriptionLY2584702tosylate
- Packaging1mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0229
- Product descriptionLY2584702 tosylate 99%
- Packaging50mg
- Price$73
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBISN0229
- Product descriptionLY2584702tosylate
- Packaging5mg
- Price$131
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0229
- Product descriptionLY2584702tosylate
- Packaging10mg
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-12493A
- Product descriptionLY-2584702tosylatesalt 99.50%
- Packaging25mg
- Price$285
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12493A
- Product descriptionLY-2584702tosylatesalt 99.50%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$111
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12493A
- Product descriptionLY-2584702tosylatesalt 99.50%
- Packaging10mM*1mLinDMSO(Solution)
- Price$116
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S7704
- Product descriptionLY2584702 Tosylate 99.57%
- Packaging10mg
- Price$140
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12493A
- Product descriptionLY-2584702tosylatesalt 99.50%
- Packaging10mg
- Price$143
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TJO | 4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99% | 1mg | $10 | 2026-05-28 | Buy |
| aablocks | AA008TJO | 4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99% | 5mg | $11 | 2026-05-28 | Buy |
| aablocks | AA008TJO | 4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99% | 10mg | $14 | 2026-05-28 | Buy |
| aablocks | AA008TJO | 4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99% | 25mg | $30 | 2026-05-28 | Buy |
| aablocks | AA008TJO | 4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate 99% | 50mg | $46 | 2026-05-28 | Buy |
| aablocks | AA008TJO | 4-(4-(4-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-1-Methyl-1H-Imidazol-2-Yl)Piperidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine 4-Methylbenzenesulfonate ≥99% | 100mg | $90 | 2026-05-28 | Buy |
| AK Scientific | 3528DG | LY-2584702(tosylatesalt) | 50mg | $735 | 2021-12-16 | Buy |
| Apolloscientific | BISN0229 | LY2584702tosylate | 1mg | $73 | 2021-12-16 | Buy |
| Apolloscientific | BISN0229 | LY2584702 tosylate 99% | 50mg | $73 | 2026-06-04 | Buy |
| Apolloscientific | BISN0229 | LY2584702tosylate | 5mg | $131 | 2021-12-16 | Buy |
| Apolloscientific | BISN0229 | LY2584702tosylate | 10mg | $203 | 2021-12-16 | Buy |
| Arctom | HY-12493A | LY-2584702tosylatesalt 99.50% | 25mg | $285 | 2026-05-26 | Buy |
| Arctom | HY-12493A | LY-2584702tosylatesalt 99.50% | 10mM*1mLinDMSO(Solid+Solvent) | $111 | 2026-05-26 | Buy |
| Arctom | HY-12493A | LY-2584702tosylatesalt 99.50% | 10mM*1mLinDMSO(Solution) | $116 | 2026-05-26 | Buy |
| Arctom | SLK-S7704 | LY2584702 Tosylate 99.57% | 10mg | $140 | 2026-05-26 | Buy |
| Arctom | HY-12493A | LY-2584702tosylatesalt 99.50% | 10mg | $143 | 2026-05-26 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:12.55(Max Conc. mg/mL);20.31(Max Conc. mM)
form :A crystalline solid
color :Light yellow to yellow
InChIKey :HDYUXDNMHBQKAU-UHFFFAOYSA-N
SMILES :FC(F)(F)c2c(ccc(c2)c3nc([n](c3)C)C4CCN(CC4)c5ncnc6n[nH]cc65)F.[S](=O)(=O)(O)c1ccc(cc1)C
solubility :DMSO:12.55(Max Conc. mg/mL);20.31(Max Conc. mM)
form :A crystalline solid
color :Light yellow to yellow
InChIKey :HDYUXDNMHBQKAU-UHFFFAOYSA-N
SMILES :FC(F)(F)c2c(ccc(c2)c3nc([n](c3)C)C4CCN(CC4)c5ncnc6n[nH]cc65)F.[S](=O)(=O)(O)c1ccc(cc1)C
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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| Precautionary statements: |
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Description
p70 Ribosomal S6 kinase (p70S6K) is a serine/threonine kinase that is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. LY2584702 is a selective, cell-permeable p70S6K inhibitor (IC50 = 4 nM). It blocks phosphorylation of p70S6K in primary rat hepatocytes without affecting the phosphorylation of other signaling kinases, including GSK-3β and ERK1/2. LY2584702 inhibits phosphorylation of p70S6K in HCT116 colon cancer cells (IC50 = 0.1-0.24 μM in vitro) and demonstrates significant antitumor efficacy in both U87MG glioblastoma and HCT116 colon carcinoma xenograft models. It also reverses the effects of mTORC1 hyperactivation on triglyceride metabolism in human hepatoma cells. LY2584702, alone or in combination with the mTOR inhibitor everolimus , has been evaluated in clinical trials against solid tumors.Related product price
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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