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ChemicalBook >> CAS DataBase List >> LY 2874455

LY 2874455

$13 - $8042
Product name: LY 2874455
CAS: 1254473-64-7
MF: C21H19Cl2N5O2
MW: 444.31
EINECS:
MDL Number:MFCD22124884
Synonyms:LY 2874455;(R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol;4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol;LY2874455/LY-2874455;4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol LY2874455;(R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethan-1-ol;(R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)-ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl);(E)-2-(4-(2-(5-(1-(3,5-DICHLOROPYRIDIN-4-YL)ETHOXY)-1H-INDAZOL-3-YL)VINYL)-1H-PYRAZOL-1-YL)ETHANOL

Price73 Properties Safety Information Description

73 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
TRC
Usbiological

Package

2mg
5mg
10mM(in1mLDMSO)
1mg
10mM(in 1mL DMSO)
10mM*1mLinDMSO
10mg
10.00mg
25.00mg
25mg
50.00mg
50mg
100mg
200mg
250mg
1g
1000mg
5g

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging25mg
Price$93
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging50mg
Price$155
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging100mg
Price$261
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging10mg
Price$46
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging5mg
Price$30
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging1mg
Price$13
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000NLZ
Product description4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%
Packaging250mg
Price$482
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberY227451
Product descriptionLY2874455 97.00%
Packaging100MG
Price$390
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberY227451
Product descriptionLY2874455 97.00%
Packaging25MG
Price$135
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2529AH
Product description(R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol
Packaging1g
Price$3047
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2529AH
Product description(R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol
Packaging5g
Price$8042
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3576
Product descriptionLY2874455
Packaging100mg
Price$462
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3576
Product descriptionLY2874455
Packaging10mM(in 1mL DMSO)
Price$200
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3576
Product descriptionLY2874455
Packaging5mg
Price$77
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3576
Product descriptionLY2874455
Packaging10mM(in1mLDMSO)
Price$88
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3576
Product descriptionLY2874455
Packaging25mg
Price$220
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	25mg	$93	2026-05-25	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	50mg	$155	2026-05-25	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	100mg	$261	2026-05-25	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	10mg	$46	2026-05-25	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	5mg	$30	2026-05-25	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	1mg	$13	2026-05-25	Buy
aablocks	AA000NLZ	4-[(1E)-2-[5-[(1R)-1-(3,5-Dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]ethenyl]-1H-pyrazole-1-ethanol 98%	250mg	$482	2026-05-25	Buy
ACHEMBLOCK	Y227451	LY2874455 97.00%	100MG	$390	2026-05-27	Buy
ACHEMBLOCK	Y227451	LY2874455 97.00%	25MG	$135	2026-05-27	Buy
AK Scientific	2529AH	(R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol	1g	$3047	2021-12-16	Buy
AK Scientific	2529AH	(R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol	5g	$8042	2021-12-16	Buy
ApexBio Technology	A3576	LY2874455	100mg	$462	2026-05-06	Buy
ApexBio Technology	A3576	LY2874455	10mM(in 1mL DMSO)	$200	2021-12-16	Buy
ApexBio Technology	A3576	LY2874455	5mg	$77	2026-05-06	Buy
ApexBio Technology	A3576	LY2874455	10mM(in1mLDMSO)	$88	2026-05-06	Buy
ApexBio Technology	A3576	LY2874455	25mg	$220	2026-05-06	Buy

Next Last

Properties

Boiling point :672.6±55.0 °C(Predicted)
Density :1.44
storage temp. :Store at -20°C
solubility :≥44.4 mg/mL in DMSO; insoluble in H2O; ≥6.34 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :12.93±0.40(Predicted)
color :Pink to gray
CAS DataBase Reference :1254473-64-7

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.

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Suppliers and manufacturers

career henan chemical co

$2.00
LY 2874455 CAS:1254473-64-7

TargetMol Chemicals Inc.

$42.00
LY2874455 CAS:1254473-64-7

Capot Chemical Co.,Ltd.

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Dideu Industries Group Limited

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

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Chemtour Biotech Co., Ltd

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LY 2874455

Properties

Safety Information

Description

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