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ChemicalBook >> CAS DataBase List >> 5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine

5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine

$15 - $4620
Product name: 5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine
CAS: 1224844-38-5
MF: C15H15N7O
MW: 309.33
EINECS:
MDL Number:MFCD22124893
Synonyms:5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine;3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;3-(2-aminobenzo[d]oxazol-5-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;INK-128 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine;-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine;INK 128 (MLN0128);INK128, >=98%

Price99 Properties Safety Information Description

99 prices

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Brand

aablocks
ACHEMBLOCK
Acrotein
Adipogen Life Sciences
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
TRC

Package

2mg
200mg
500mg
1000mg
10mM(in 1mL DMSO)
2.00g
10mM*1mLinDMSO
2g
5.00g
10.00g
10mM(in1mLDMSO)
1mg
5mg
10mg
25mg
50mg
100mg
0.1g
0.25g
250mg
1G

Manufactureraablocks
Product numberAA00177U
Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ≥98%
Packaging5mg
Price$15
Updated2026-05-28
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Manufactureraablocks
Product numberAA00177U
Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ≥98%
Packaging25mg
Price$53
Updated2026-05-28
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Manufactureraablocks
Product numberAA00177U
Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 99%
Packaging100mg
Price$147
Updated2026-05-28
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Manufactureraablocks
Product numberAA00177U
Product description3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 99%
Packaging250mg
Price$296
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberL21907
Product descriptionSapanisertib 98%
Packaging100MG
Price$130
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberL21907
Product descriptionSapanisertib 98%
Packaging100MG
Price$130
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberL21907
Product descriptionSapanisertib 98%
Packaging1G
Price$830
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberL21907
Product descriptionSapanisertib 98%
Packaging1G
Price$830
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberL21907
Product descriptionSapanisertib 98%
Packaging25MG
Price$50
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberL21907
Product descriptionSapanisertib 98%
Packaging25MG
Price$50
Updated2026-05-27
Buy

ManufacturerAcrotein
Product numberUT00151
Product description5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97%
Packaging0.1g
Price$183.33
Updated2021-12-16
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ManufacturerAcrotein
Product numberUT00151
Product description5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97%
Packaging0.25g
Price$383.33
Updated2021-12-16
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ManufacturerAdipogen Life Sciences
Product numberSYN-1157-M050
Product descriptionMLN0128 ≥95%
Packaging50mg
Price$1004
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1157-M001
Product descriptionMLN0128 ≥95%
Packaging1mg
Price$103
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1157-M005
Product descriptionMLN0128 ≥95%
Packaging5mg
Price$173
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1157-M010
Product descriptionMLN0128 ≥95%
Packaging10mg
Price$281
Updated2026-05-06
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Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00177U	3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ≥98%	5mg	$15	2026-05-28	Buy
aablocks	AA00177U	3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ≥98%	25mg	$53	2026-05-28	Buy
aablocks	AA00177U	3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 99%	100mg	$147	2026-05-28	Buy
aablocks	AA00177U	3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 99%	250mg	$296	2026-05-28	Buy
ACHEMBLOCK	L21907	Sapanisertib 98%	100MG	$130	2026-05-25	Buy
ACHEMBLOCK	L21907	Sapanisertib 98%	100MG	$130	2026-05-27	Buy
ACHEMBLOCK	L21907	Sapanisertib 98%	1G	$830	2026-05-25	Buy
ACHEMBLOCK	L21907	Sapanisertib 98%	1G	$830	2026-05-27	Buy
ACHEMBLOCK	L21907	Sapanisertib 98%	25MG	$50	2026-05-25	Buy
ACHEMBLOCK	L21907	Sapanisertib 98%	25MG	$50	2026-05-27	Buy
Acrotein	UT00151	5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97%	0.1g	$183.33	2021-12-16	Buy
Acrotein	UT00151	5-(4-Amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine 97%	0.25g	$383.33	2021-12-16	Buy
Adipogen Life Sciences	SYN-1157-M050	MLN0128 ≥95%	50mg	$1004	2026-05-06	Buy
Adipogen Life Sciences	SYN-1157-M001	MLN0128 ≥95%	1mg	$103	2026-05-06	Buy
Adipogen Life Sciences	SYN-1157-M005	MLN0128 ≥95%	5mg	$173	2026-05-06	Buy
Adipogen Life Sciences	SYN-1157-M010	MLN0128 ≥95%	10mg	$281	2026-05-06	Buy

Next Last

Properties

Melting point :270-272°C (dec.)
Boiling point :598.8±60.0 °C(Predicted)
Density :1.64
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
pka :3.77±0.30(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
InChIKey :GYLDXIAOMVERTK-UHFFFAOYSA-N
SMILES :C1=NC(N)=C2C(C3=CC=C4OC(N)=NC4=C3)=NN(C(C)C)C2=N1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H303	May be harmfulif swallowed	Acute toxicity,oral	Category 5			P312
H320	Causes eye irritation	Serious eye damage/eye irritation	Category 2B	Warning		P264, P305+P351+P338,P337+P313

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313	IF eye irritation persists: Get medical advice/attention.

Description

The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TORC1/2, acting as a sub-nanomolar ATP-dependent inhibitor of mTOR kinase. It blocks the phosphorylation of downstream substrates of both TORC1 and TORC2. INK128 interferes with the growth of cell lines which are resistant to rapamycin and pan-PI3K inhibitors. Moreover, daily, oral administration of INK128 inhibits angiogenesis and tumor growth in several xenograft models. The effects of INK128 on gene expression also reduce invasion and metastasis.

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Suppliers and manufacturers

career henan chemical co

$2.00
5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine CAS:1224844-38-5

TargetMol Chemicals Inc.

$34.00
Sapanisertib CAS:1224844-38-5

Wuhan Nutra Biotechnology Co.,Ltd

Sapanisertib;MLN0218 CAS:1224844-38-5

ATK CHEMICAL COMPANY LIMITED

CONIER CHEM AND PHARMA LIMITED

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd

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Dideu Industries Group Limited

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5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers