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ChemicalBook >> CAS DataBase List >> N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide

N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide

N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide price.
  • $44 - $2053
  • Product name: N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide
  • CAS: 1346528-50-4
  • MF: C18H17ClF2N4O3
  • MW: 410.8
  • EINECS:-0
  • MDL Number:MFCD29047142
  • Synonyms:N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide;N-(4-Chloro-3-pyridinyl)-4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-1-piperazinecarboxamide;JNJ42165279;CS-2830;JNJ 42165279;JNJ42165279;1-Piperazinecarboxamide, N-(4-chloro-3-pyridinyl)-4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-;JNJ-42165279 (JNJ-5279);Fatty acid amide hydrolase,inhibit,Autophagy,JNJ 42165279,FAAH,JNJ-42165279,Inhibitor
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 10mM*1mLinDMSO(Solution)
  • 2mg
  • 5mg
  • 10.00mg
  • 10mg
  • 25mg
  • 25.00mg
  • 50mg
  • 50.00mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide ≥98%
  • Packaging1mg
  • Price$49
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging2mg
  • Price$51
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging10mg
  • Price$91
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging5mg
  • Price$68
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging25mg
  • Price$159
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging50mg
  • Price$228
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging100mg
  • Price$326
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide
  • Packaging200mg
  • Price$452
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CI7
  • Product descriptionN-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 98%
  • Packaging1g
  • Price$2053
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberP50899
  • Product descriptionJNJ-42165279 98%
  • Packaging100MG
  • Price$80
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberP50899
  • Product descriptionJNJ-42165279 98%
  • Packaging100MG
  • Price$80
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberP50899
  • Product descriptionJNJ-42165279 98%
  • Packaging1G
  • Price$520
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberP50899
  • Product descriptionJNJ-42165279 98%
  • Packaging1G
  • Price$520
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number7849DL
  • Product descriptionN-(4-Chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide
  • Packaging5mg
  • Price$289
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC4122
  • Product descriptionJNJ-42165279
  • Packaging10mg
  • Price$291
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC4122
  • Product descriptionJNJ-42165279
  • Packaging25mg
  • Price$546
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide ≥98% 1mg $49 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 2mg $51 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 10mg $91 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 5mg $68 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 25mg $159 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 50mg $228 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 100mg $326 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 200mg $452 2026-05-28 Buy
aablocks AA009CI7 N-(4-Chloropyridin-3-Yl)-4-((2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl)Methyl)Piperazine-1-Carboxamide 98% 1g $2053 2026-05-28 Buy
ACHEMBLOCK P50899 JNJ-42165279 98% 100MG $80 2026-05-25 Buy
ACHEMBLOCK P50899 JNJ-42165279 98% 100MG $80 2026-05-27 Buy
ACHEMBLOCK P50899 JNJ-42165279 98% 1G $520 2026-05-25 Buy
ACHEMBLOCK P50899 JNJ-42165279 98% 1G $520 2026-05-27 Buy
AK Scientific 7849DL N-(4-Chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide 5mg $289 2021-12-16 Buy
ApexBio Technology C4122 JNJ-42165279 10mg $291 2021-12-16 Buy
ApexBio Technology C4122 JNJ-42165279 25mg $546 2021-12-16 Buy

Properties

Boiling point :541.2±50.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
pka :12.91±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

JNJ-42165279 is a potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH; IC50s = 70 and 313 nM for human and rat forms, respectively). It displays selectivity for FAAH over a panel of other enzymes, receptors, transporters, and ion channels. JNJ-42165279 is active in vivo, blocking FAAH activity in brain and periphery of rats and raising concentrations of anandamide , oleoyl ethanolamide , and palmitoyl ethanolamide . It is also efficacious in the spinal nerve ligation model of neuropathic pain.

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