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ChemicalBook >> CAS DataBase List >> 4SC-202

4SC-202

4SC-202 price.
  • $48 - $2691.1
  • Product name: 4SC-202
  • CAS: 1186222-89-8
  • MF: C30H29N5O6S2
  • MW: 619.71116
  • EINECS:
  • MDL Number:MFCD25976779
  • Synonyms:4SC-202;4SC-202 2-Propenamide, N-(2-aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-, (2E)-, 4-methylbenzenesul;(E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide 4-methylbenzenesulfonate;4SC-202 tosylate;CS-1272;Domatinostat tosylate;4SC-202;4SC202;4SC 202;Domatinostat tosylate,Domatinostat,Apoptosis,inhibit,Histone deacetylases,Inhibitor,HDAC
58 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • Manufactureraablocks
  • Product numberAA008T9V
  • Product description(2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate
  • Packaging1mg
  • Price$48
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008T9V
  • Product description(2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate
  • Packaging5mg
  • Price$85
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008T9V
  • Product description(2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate
  • Packaging10mg
  • Price$119
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008T9V
  • Product description(2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate
  • Packaging25mg
  • Price$203
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008T9V
  • Product description(2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate
  • Packaging100mg
  • Price$467
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008T9V
  • Product description(2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate
  • Packaging50mg
  • Price$318
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number2836DF
  • Product description4SC-202
  • Packaging25mg
  • Price$721
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging100mg
  • Price$670
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging10mg
  • Price$171
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging50mg
  • Price$462
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging5mg
  • Price$111
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4106
  • Product description4SC-202
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-16012
  • Product descriptionDomatinostattosylate 98.90%
  • Packaging10mg
  • Price$143
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008T9V (2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate 1mg $48 2026-05-28 Buy
aablocks AA008T9V (2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate 5mg $85 2026-05-28 Buy
aablocks AA008T9V (2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate 10mg $119 2026-05-28 Buy
aablocks AA008T9V (2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate 25mg $203 2026-05-28 Buy
aablocks AA008T9V (2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate 100mg $467 2026-05-28 Buy
aablocks AA008T9V (2E)-N-(2-Aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-2-propenamide 4-methylbenzenesulfonate 50mg $318 2026-05-28 Buy
AK Scientific 2836DF 4SC-202 25mg $721 2021-12-16 Buy
ApexBio Technology B4106 4SC-202 100mg $700 2021-12-16 Buy
ApexBio Technology B4106 4SC-202 50mg $450 2021-12-16 Buy
ApexBio Technology B4106 4SC-202 5mg $100 2021-12-16 Buy
ApexBio Technology B4106 4SC-202 100mg $670 2026-05-06 Buy
ApexBio Technology B4106 4SC-202 10mg $171 2026-05-06 Buy
ApexBio Technology B4106 4SC-202 50mg $462 2026-05-06 Buy
ApexBio Technology B4106 4SC-202 5mg $111 2026-05-06 Buy
ApexBio Technology B4106 4SC-202 10mg $150 2021-12-16 Buy
Arctom HY-16012 Domatinostattosylate 98.90% 10mg $143 2026-05-26 Buy

Properties

storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥2.4 mg/mL in EtOH with gentle warming and ultrasonic; ≥62 mg/mL in DMSO
form :Powder
color :Light yellow to brown

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P311 Call a POISON CENTER or doctor/physician.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P361 Remove/Take off immediately all contaminated clothing.
P362 Take off contaminated clothing and wash before reuse.
P363 Wash contaminated clothing before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4SC-202 is an inhibitor of the class I histone deacetylases (HDACs) HDAC1-3 and the histone demethylase KDM1A. It reduces cell viability in a panel of colorectal cancer (CRC) cell lines when used at concentrations ranging from 1 to 10 μM and in patient-derived CRC cell lines when used at a concentration of 5 μM. 4SC-202 (5 μM) induces cell cycle arrest at the G2/M phase in HT-29 cells and primary human CRC cells and increases apoptosis in HT-29 cells in a concentration-dependent manner, an effect that is enhanced by the Akt inhibitors perifosine and MK-2206 . 4SC-202 (100 mg/kg, p.o., every other day) reduces tumor growth in an HT-29 mouse xenograft model when administered alone and to an enhanced degree when co-administered with oxaliplatin (Item No. 13106).

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