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ChemicalBook >> CAS DataBase List >> (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE

(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE

(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE price.
  • $19 - $2065
  • Product name: (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE
  • CAS: 66701-25-5
  • MF: C15H27N5O5
  • MW: 357.41
  • EINECS:613-978-4
  • MDL Number:MFCD07366493
  • Synonyms:(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid;proteinaseinhibitore64 ;thiolproteaseinhibitor ;TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-*(4-GU ANIDINO)BUT;(2S, 3S)-TRANS-EPOXY SUCCINYL-L-LEUCYLAMIDO-(4-GUANIDINO) BUTANE;L-TRANS-EPOXYSUCCINYL-LEU-AGMATINE;E-64, L-trans-Epoxysuccinyl-Leu-agMatine;TRANS-EPOXYSUCCINYL-LEUCYLAMIDO-[4-GUANIDINO]BUTANE
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  • aablocks
  • ACHEMBLOCK
  • Acrotein
  • Adipogen Life Sciences
  • AK Scientific
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  • EvaluationSample
  • 10mM(in1mLDMSO)
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99%
  • Packaging1mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99%
  • Packaging5mg
  • Price$35
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99%
  • Packaging10mg
  • Price$59
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99%
  • Packaging25mg
  • Price$125
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99%
  • Packaging50mg
  • Price$209
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99
  • Packaging100mg
  • Price$303
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0036QT
  • Product descriptionE-64 99
  • Packaging500mg
  • Price$686
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238714
  • Product descriptionE-64 98%
  • Packaging250MG
  • Price$845
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238714
  • Product descriptionE-64 98%
  • Packaging100MG
  • Price$340
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238714
  • Product descriptionE-64 98%
  • Packaging25MG
  • Price$150
  • Updated2026-05-27
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  • ManufacturerAcrotein
  • Product numberAS04263
  • Product descriptionE-64 97%
  • Packaging0.25g
  • Price$443.5
  • Updated2026-05-25
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  • ManufacturerAcrotein
  • Product numberAS04263
  • Product descriptionE-64 97%
  • Packaging0.1g
  • Price$266.1
  • Updated2026-05-25
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  • ManufacturerAcrotein
  • Product numberAS04263
  • Product descriptionE-64 97%
  • Packaging0.5g
  • Price$745.1
  • Updated2026-05-25
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CP3-7006-M100
  • Product descriptionE-64 ≥98%(HPLC)
  • Packaging100mg
  • Price$690
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CP3-7006-M025
  • Product descriptionE-64 ≥98%(HPLC)
  • Packaging25mg
  • Price$200
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CP3-7006-M005
  • Product descriptionE-64 ≥98%(HPLC)
  • Packaging5mg
  • Price$50
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0036QT E-64 99% 1mg $19 2026-05-28 Buy
aablocks AA0036QT E-64 99% 5mg $35 2026-05-28 Buy
aablocks AA0036QT E-64 99% 10mg $59 2026-05-28 Buy
aablocks AA0036QT E-64 99% 25mg $125 2026-05-28 Buy
aablocks AA0036QT E-64 99% 50mg $209 2026-05-28 Buy
aablocks AA0036QT E-64 99 100mg $303 2026-05-28 Buy
aablocks AA0036QT E-64 99 500mg $686 2026-05-28 Buy
ACHEMBLOCK Z238714 E-64 98% 250MG $845 2026-05-27 Buy
ACHEMBLOCK Z238714 E-64 98% 100MG $340 2026-05-27 Buy
ACHEMBLOCK Z238714 E-64 98% 25MG $150 2026-05-27 Buy
Acrotein AS04263 E-64 97% 0.25g $443.5 2026-05-25 Buy
Acrotein AS04263 E-64 97% 0.1g $266.1 2026-05-25 Buy
Acrotein AS04263 E-64 97% 0.5g $745.1 2026-05-25 Buy
Adipogen Life Sciences AG-CP3-7006-M100 E-64 ≥98%(HPLC) 100mg $690 2026-05-06 Buy
Adipogen Life Sciences AG-CP3-7006-M025 E-64 ≥98%(HPLC) 25mg $200 2026-05-06 Buy
Adipogen Life Sciences AG-CP3-7006-M005 E-64 ≥98%(HPLC) 5mg $50 2026-05-06 Buy

Properties

Melting point :>170°C (dec.)
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: 20 mg/mL, clear, colorless
pka :3.16±0.40(Predicted)
form :White solid
color :White or off-white
biological source :synthetic (organic)
Water Solubility :Soluble in DMSO (25mg/ml), or water (20mg/ml)
Sensitive :Light Sensitive
BRN :1405664
Stability :Stable for 1 year from date of purchase as supplied.
InChIKey :LTLYEAJONXGNFG-DCAQKATOSA-N
SMILES :O1[C@H](C(N[C@H](C(NCCCCNC(N)=N)=O)CC(C)C)=O)[C@H]1C(O)=O
CAS DataBase Reference :66701-25-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

It is used as a broad spectrum cysteine proteinase and calpain activation inhibitor. Additionally, Prevotella intermediate studies report that E-64 blocks the breakdown of methaemoglobin and the oxidation of oxyhaemoglobin by InpA. E-64 has also been used to study excystation in Giardia lamblia. E-64 is an inhibitor of Calpain, cathepsin K and cathepsin S. E-64 is an effective ligand for affinity purification of cysteine proteases. When coupled to a thiolated affinity matrix, binding is no longer irreversible, but specificity is retained

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