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ChemicalBook >> CAS DataBase List >> ACTINONIN

ACTINONIN

ACTINONIN price.
  • $44 - $4350
  • Product name: ACTINONIN
  • CAS: 13434-13-4
  • MF: C19H35N3O5
  • MW: 385.5
  • EINECS:
  • MDL Number:MFCD00058569
  • Synonyms:(-)-ACTINONIN;3-[[1-[[2-(HYDROXYMETHYL)-1-PYRROLIDINYL]CARBONYL]-2-METHYL-PROPYL]CARBAMOYL]OCTANOHYDROXAMIC ACID;3-[[1-[[2-(HYDROXYMETHYL)-1-PYRROLIDINYL]-CARBONYL]-2-METHYLPROPYL]-CARBAMOYL]-OCTONOHYDROXAMIC ACID;N4-HYDROXY-N1-[(1S)-1[[(2S)-2-(HYDROXYMETHYL)-1-PYRROLDINYL]CARBONYL]-2-METHYLPROPYL]-2-PENTYL-,(2R)-(9CI);hylpropyl)carbamoyl)- ;octanohydroxamicacid,3-((1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2-met ;N'-Hydroxy-N-[1-[[2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentylbutanediamide;(2R)-2-[2-(hydroxyamino)-2-keto-ethyl]-N-[(1S)-2-methyl-1-[(2S)-2-methylolpyrrolidine-1-carbonyl]propyl]enanthamide
55 prices
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Brand
  • aablocks
  • Adipogen Life Sciences
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 2mg
  • 2.5mg
  • 1mg
  • 1mlx10mM(inDMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA007ZY4
  • Product descriptionActinonin 95%
  • Packaging1mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007ZY4
  • Product descriptionActinonin 95%
  • Packaging5mg
  • Price$53
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007ZY4
  • Product descriptionActinonin 95%
  • Packaging10mg
  • Price$95
  • Updated2026-05-28
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0161-M005
  • Product descriptionActinonin >97.0%(HPLC)
  • Packaging5mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0161-M005
  • Product descriptionActinonin >97.0%(HPLC)
  • Packaging5mg
  • Price$95
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0161-M025
  • Product descriptionActinonin >97.0%(HPLC)
  • Packaging25mg
  • Price$380
  • Updated2026-05-06
  • Buy
  • ManufacturerAmbeed
  • Product numberA236595
  • Product descriptionActinonin 95%
  • Packaging1mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3331
  • Product descriptionActinonin
  • Packaging5mg
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3331
  • Product descriptionActinonin
  • Packaging25mg
  • Price$516
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging50mg
  • Price$369
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging50mg
  • Price$369
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging25mg
  • Price$206
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging25mg
  • Price$206
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging10mg
  • Price$98
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging10mg
  • Price$98
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberBD-A236595
  • Product descriptionActinonin 95%
  • Packaging5mg
  • Price$55
  • Updated2026-05-25
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA007ZY4 Actinonin 95% 1mg $44 2026-05-28 Buy
aablocks AA007ZY4 Actinonin 95% 5mg $53 2026-05-28 Buy
aablocks AA007ZY4 Actinonin 95% 10mg $95 2026-05-28 Buy
Adipogen Life Sciences AG-CN2-0161-M005 Actinonin >97.0%(HPLC) 5mg $98 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0161-M005 Actinonin >97.0%(HPLC) 5mg $95 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0161-M025 Actinonin >97.0%(HPLC) 25mg $380 2026-05-06 Buy
Ambeed A236595 Actinonin 95% 1mg $76 2021-12-16 Buy
ApexBio Technology C3331 Actinonin 5mg $121 2021-12-16 Buy
ApexBio Technology C3331 Actinonin 25mg $516 2021-12-16 Buy
Arctom BD-A236595 Actinonin 95% 50mg $369 2026-05-25 Buy
Arctom BD-A236595 Actinonin 95% 50mg $369 2026-05-26 Buy
Arctom BD-A236595 Actinonin 95% 25mg $206 2026-05-25 Buy
Arctom BD-A236595 Actinonin 95% 25mg $206 2026-05-26 Buy
Arctom BD-A236595 Actinonin 95% 10mg $98 2026-05-25 Buy
Arctom BD-A236595 Actinonin 95% 10mg $98 2026-05-26 Buy
Arctom BD-A236595 Actinonin 95% 5mg $55 2026-05-25 Buy

Properties

Melting point :137-139°C
Density :1.139±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
pka :9.19±0.20(Predicted)
form :White to off-white powder.
color :White
biological source :synthetic (organic)
BRN :1555250
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChI :1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
InChIKey :XJLATMLVMSFZBN-UHFFFAOYSA-N
SMILES :CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
CAS DataBase Reference :13434-13-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Actinonin is a peptidomimetic antibiotic produced by Actinomyces that inhibits aminopeptidases. It inhibits the following matrix metalloproteinases (MMPs): MMP-1 (Ki = 300 nM), MMP-2 (IC50 = ~90 nM), MMP-3 (Ki = 1,700 nM), MMP-7 (IC50 = ~3,500 nM), MMP-8 (Ki = 130 nM), MMP-9 (Ki = 330 nM), MMP-10 (IC50 = ~500 nM), MMP-12 (IC50 = ~350 nM), and MMP-13 (IC50 = ~100 nM), but not MMP-14 (IC50 > 1 mM). Actinonin acts as an herbicide by targeting plastid peptide deformylase, an enzyme required for N-terminal processing of plastid-encoded proteins. Actinonin has also been identified as an effective inhibitor of human meprin α (Ki = 20 nM), a zinc endopeptidase that cleaves matrix proteins. More recently actinonin has been shown to inhibit tumor cell invasion and matrix degradation and to induce apoptosis in animal models by targeting human mitochondrial peptide deformylase.

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