Allopregnanolone
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- $40 - $2160
- Product name: Allopregnanolone
- CAS: 516-54-1
- MF: C21H34O2
- MW: 318.49
- EINECS:687-782-2
- MDL Number:MFCD00003677
- Synonyms:1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone;3-A-5-A-TETRAHYDROPROGESTERONE;3-alpha,5-alpha-pregnanolone ;3α-OH-DHP;Allopregnan-3a-ol-20-one;(3α)-Allopregnanolone;3α,5α-Tetrahydroprogesterone;3α,5α-THP
43 prices
Selected condition：
Brand
- AHH
- ApexBio Technology
- AvaChem
- Biosynth
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 0.05g
- 0.1g
- 100mg
- 200ul
- 0.25g
- 250mg
- 0.5g
- 1g
- 2g
- ManufacturerAHH
- Product numberMT-46773
- Product descriptionAllopregnanolone 97%
- Packaging0.05g
- Price$380
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-46773
- Product descriptionAllopregnanolone 97%
- Packaging0.05g
- Price$380
- Updated2026-05-26
- Buy
- ManufacturerApexBio Technology
- Product numberB7456
- Product descriptionAllopregnanolone
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number6081
- Product descriptionAllopregnanolone 98%
- Packaging100mg
- Price$279
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6081
- Product descriptionAllopregnanolone 98%
- Packaging5mg
- Price$59
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6081
- Product descriptionAllopregnanolone 98%
- Packaging10mg
- Price$89
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6081
- Product descriptionAllopregnanolone 98%
- Packaging25mg
- Price$129
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6081
- Product descriptionAllopregnanolone 98%
- Packaging1g
- Price$1279
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging1g
- Price$1435.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging25mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging10mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging50mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging100mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging0.1g
- Price$508.81
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging250mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA158661
- Product description5alpha-Pregnan-3a-ol-20-one
- Packaging0.25g
- Price$850.93
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-46773 | Allopregnanolone 97% | 0.05g | $380 | 2026-05-25 | Buy |
| AHH | MT-46773 | Allopregnanolone 97% | 0.05g | $380 | 2026-05-26 | Buy |
| ApexBio Technology | B7456 | Allopregnanolone | 10mg | $140 | 2021-12-16 | Buy |
| AvaChem | 6081 | Allopregnanolone 98% | 100mg | $279 | 2026-05-22 | Buy |
| AvaChem | 6081 | Allopregnanolone 98% | 5mg | $59 | 2026-05-22 | Buy |
| AvaChem | 6081 | Allopregnanolone 98% | 10mg | $89 | 2026-05-22 | Buy |
| AvaChem | 6081 | Allopregnanolone 98% | 25mg | $129 | 2026-05-22 | Buy |
| AvaChem | 6081 | Allopregnanolone 98% | 1g | $1279 | 2026-05-22 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 1g | $1435.5 | 2026-06-04 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 25mg | $80 | 2021-12-16 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 10mg | $55 | 2021-12-16 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 50mg | $120 | 2021-12-16 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 100mg | $200 | 2021-12-16 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 0.1g | $508.81 | 2026-06-04 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 250mg | $325 | 2021-12-16 | Buy |
| Biosynth | FA158661 | 5alpha-Pregnan-3a-ol-20-one | 0.25g | $850.93 | 2026-06-04 | Buy |
Properties
Melting point :176-178°
alpha :D +87.7° (abs alc)
Boiling point :431.2±18.0 °C(Predicted)
Density :1.053±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :chloroform: 20 mg/mL, clear, colorless
pka :15.12±0.70(Predicted)
form :White solid
color :white
Merck :13,272
BRN :3211363
Stability :Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :InChI=1/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/s3
InChIKey :AURFZBICLPNKBZ-SYBPFIFISA-N
SMILES :[C@]12([H])CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CC[C@@]1([H])C[C@H](O)CC[C@]21C)C(=O)C |&1:0,4,6,9,11,15,18,22,r|
CAS DataBase Reference :516-54-1(CAS DataBase Reference)
alpha :D +87.7° (abs alc)
Boiling point :431.2±18.0 °C(Predicted)
Density :1.053±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :chloroform: 20 mg/mL, clear, colorless
pka :15.12±0.70(Predicted)
form :White solid
color :white
Merck :13,272
BRN :3211363
Stability :Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :InChI=1/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/s3
InChIKey :AURFZBICLPNKBZ-SYBPFIFISA-N
SMILES :[C@]12([H])CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CC[C@@]1([H])C[C@H](O)CC[C@]21C)C(=O)C |&1:0,4,6,9,11,15,18,22,r|
CAS DataBase Reference :516-54-1(CAS DataBase Reference)
Safety Information
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Description
Allopregnanolone is an endogenous inhibitory pregnane neurosteroid that is synthesized from progesterone . It acts as a positive allosteric modulator of GABAA receptors at nM concentrations (exhibiting the greatest potentiation at isoforms containing δ subunits) and of GABAC receptors at μM concentrations. Allopregnanolone displays effects similar to other GABAA receptor potentiators such as benzodiazepines, including potent anticonvulsant, anxiolytic, and sedative activity.Related product price
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