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ChemicalBook >> CAS DataBase List >> Alvespimycin

Alvespimycin

Alvespimycin price.
  • $30 - $2658
  • Product name: Alvespimycin
  • CAS: 467214-20-6
  • MF: C32H48N4O8
  • MW: 616.75
  • EINECS:
  • MDL Number:MFCD08457919
  • Synonyms:17-DIMETHYLAMINOETHYLAMINO-17-DEMETHOXYG;17-DMAGhydrochloride;Alvespimycin;17-DMAG (Alvespimycin);Unii-001L2fe0m3;17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycinhydrochloride;17-N-(2-DiMethylaMinoethylaMino)-17-deMethoxy GeldanaMycin;17-N-(2-DiMethylaMinoethylaMino)-17-deMethoxy GeldanaMycin-d6
55 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • American Custom Chemicals Corporation
  • Apolloscientific
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
  • Usbiological
Package
  • 100ug
  • 1mg
  • 2mg
  • 1
  • 2.5mg
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA0071YF
  • Product descriptionAlvespimycin
  • Packaging5mg
  • Price$92
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0071YF
  • Product descriptionAlvespimycin ≥98%
  • Packaging1mg
  • Price$41
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0071YF
  • Product descriptionAlvespimycin ≥98%
  • Packaging25mg
  • Price$242
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0071YF
  • Product descriptionAlvespimycin ≥98%
  • Packaging100mg
  • Price$795
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD249503
  • Product descriptionAlvespimycin 98%
  • Packaging25MG
  • Price$165
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD249503
  • Product descriptionAlvespimycin 98%
  • Packaging10MG
  • Price$105
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD249503
  • Product descriptionAlvespimycin 98%
  • Packaging100MG
  • Price$545
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0540-M001
  • Product description17-DMAG ≥98%(HPLC)
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0540-M005
  • Product description17-DMAG ≥98%(HPLC)
  • Packaging5mg
  • Price$100
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0540-M001
  • Product description17-DMAG ≥98%(HPLC)
  • Packaging1mg
  • Price$40
  • Updated2026-05-06
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0028031
  • Product description17-DIMETHYLAMINOGELDANAMYCIN 95.00%
  • Packaging5MG
  • Price$456.98
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID1002
  • Product description17-Dimethylaminoethylamino-17-demethoxygeldanamycin
  • Packaging50mg
  • Price$366
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID1002
  • Product description17-Dimethylaminoethylamino-17-demethoxygeldanamycin
  • Packaging100mg
  • Price$661
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID1002
  • Product description17-Dimethylaminoethylamino-17-demethoxygeldanamycin
  • Packaging250mg
  • Price$1462
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID1002
  • Product description17-Dimethylaminoethylamino-17-demethoxygeldanamycin
  • Packaging500mg
  • Price$2658
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBID1002
  • Product description17-Dimethylaminoethylamino-17-demethoxygeldanamycin
  • Packaging10mg
  • Price$93
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0071YF Alvespimycin 5mg $92 2026-05-28 Buy
aablocks AA0071YF Alvespimycin ≥98% 1mg $41 2026-05-28 Buy
aablocks AA0071YF Alvespimycin ≥98% 25mg $242 2026-05-28 Buy
aablocks AA0071YF Alvespimycin ≥98% 100mg $795 2026-05-28 Buy
ACHEMBLOCK AD249503 Alvespimycin 98% 25MG $165 2026-05-27 Buy
ACHEMBLOCK AD249503 Alvespimycin 98% 10MG $105 2026-05-27 Buy
ACHEMBLOCK AD249503 Alvespimycin 98% 100MG $545 2026-05-27 Buy
Adipogen Life Sciences AG-CN2-0540-M001 17-DMAG ≥98%(HPLC) 1mg $30 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0540-M005 17-DMAG ≥98%(HPLC) 5mg $100 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0540-M001 17-DMAG ≥98%(HPLC) 1mg $40 2026-05-06 Buy
American Custom Chemicals Corporation API0028031 17-DIMETHYLAMINOGELDANAMYCIN 95.00% 5MG $456.98 2021-12-16 Buy
Apolloscientific BID1002 17-Dimethylaminoethylamino-17-demethoxygeldanamycin 50mg $366 2026-06-04 Buy
Apolloscientific BID1002 17-Dimethylaminoethylamino-17-demethoxygeldanamycin 100mg $661 2026-06-04 Buy
Apolloscientific BID1002 17-Dimethylaminoethylamino-17-demethoxygeldanamycin 250mg $1462 2026-06-04 Buy
Apolloscientific BID1002 17-Dimethylaminoethylamino-17-demethoxygeldanamycin 500mg $2658 2026-06-04 Buy
Apolloscientific BID1002 17-Dimethylaminoethylamino-17-demethoxygeldanamycin 10mg $93 2026-06-04 Buy

Properties

Melting point :>270°C (dec.)
Boiling point :810.5±65.0 °C(Predicted)
Density :1.20
storage temp. :Desiccate at -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :8.48±0.70(Predicted)
color :Very Dark Purple
InChIKey :KUFRQPKVAWMTJO-NTPQRYOENA-N
SMILES :C1(NCCN(C)C)C(=O)C=C2NC(=O)C(=CC=C[C@H](OC)[C@@H](OC(=O)N)C(C)=C[C@H](C)[C@@H](O)[C@@H](OC)C[C@H](C)CC=1C2=O)C |c:16,t:14,27,&1:18,21,29,31,33,37,r|

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Geldanamycin is a potent inhibitor of Hsp90 that has poor water solubility. 17-DMAG is a water-soluble derivative of geldanamycin which potently inhibits Hsp90 (IC50 = 24 nM) and has excellent bioavailability and tissue distribution in animals. Like other Hsp90 inhibitors, 17-DMAG has diverse anti-tumor actions and has potential in treating certain types of cancer. This compound also suppresses inflammation by interfering with signaling through the NF-κB pathway. 17-DMAG also ameliorates high fat diet-induced renal failure in a mouse model of diabetes.

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