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ChemicalBook >> CAS DataBase List >> Anifostine trihydrate

Anifostine trihydrate

Anifostine trihydrate price.
  • $6 - $2159
  • Product name: Anifostine trihydrate
  • CAS: 112901-68-5
  • MF: C5H17N2O4PS
  • MW: 232.23
  • EINECS:
  • MDL Number:MFCD00233058
  • Synonyms:Amifostine (150 mg);Anifostine trihydrate;Ethanethiol,2-[(3-aMinopropyl)aMino]-, 1-(dihydrogen phosphate), hydrate (1:3);Amifostine trihydrate, >=98%;Aminopropylamino)ethylsulfanylphosphonic acid trihydrate;S-2-(3-AMINOPROPYLAMINO)ETHYL O,O-DIHYDROGEN PHOSPHOROTHIOATE;WR2721;Amifostinetrihydrateormonohydrate
71 prices
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  • aablocks
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
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  • Usbiological
Package
  • 5MG
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  • 0.1g
  • 10mM*1mLinDMSO
  • 1mg
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  • 250.00mg
  • 250mg
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  • 1.00g
  • 1g
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  • 5g
  • 5.00g
  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97%
  • Packaging1mg
  • Price$9
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97%
  • Packaging10mg
  • Price$13
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97%
  • Packaging50mg
  • Price$25
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97%
  • Packaging250mg
  • Price$47
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97%
  • Packaging100mg
  • Price$32
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97%
  • Packaging1g
  • Price$94
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HCDD
  • Product descriptionS-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate ≥97%
  • Packaging5g
  • Price$388
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number2141AH
  • Product description2-(3-Aminopropylamino)ethylsulfanylphosphonicacidtrihydrate
  • Packaging10mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA210496
  • Product descriptionAmifostine trihydrate 97%
  • Packaging1g
  • Price$37
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA210496
  • Product descriptionAmifostine trihydrate 97%
  • Packaging5g
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA210496
  • Product descriptionAmifostine trihydrate 97%
  • Packaging250mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA210496
  • Product descriptionAmifostine trihydrate 97%
  • Packaging50mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA210496
  • Product descriptionAmifostine trihydrate 97%
  • Packaging100mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0008290
  • Product description2-(3-AMINOPROPYLAMINO)ETHYLSULFANYLPHOSPHONIC ACID TRIHYDRATE 95.00%
  • Packaging5MG
  • Price$498.86
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS479328
  • Product descriptionAmifostine trihydrate 97%
  • Packaging1g
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-B0639A
  • Product descriptionAmifostine trihydrate 99.95%
  • Packaging5g
  • Price$437
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97% 1mg $9 2026-05-28 Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97% 10mg $13 2026-05-28 Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97% 50mg $25 2026-05-28 Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97% 250mg $47 2026-05-28 Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97% 100mg $32 2026-05-28 Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate 97% 1g $94 2026-05-28 Buy
aablocks AA00HCDD S-(2-((3-Aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate ≥97% 5g $388 2026-05-28 Buy
AK Scientific 2141AH 2-(3-Aminopropylamino)ethylsulfanylphosphonicacidtrihydrate 10mg $92 2021-12-16 Buy
Ambeed A210496 Amifostine trihydrate 97% 1g $37 2021-12-16 Buy
Ambeed A210496 Amifostine trihydrate 97% 5g $124 2021-12-16 Buy
Ambeed A210496 Amifostine trihydrate 97% 250mg $13 2021-12-16 Buy
Ambeed A210496 Amifostine trihydrate 97% 50mg $6 2021-12-16 Buy
Ambeed A210496 Amifostine trihydrate 97% 100mg $8 2021-12-16 Buy
American Custom Chemicals Corporation ING0008290 2-(3-AMINOPROPYLAMINO)ETHYLSULFANYLPHOSPHONIC ACID TRIHYDRATE 95.00% 5MG $498.86 2021-12-16 Buy
Arctom AS479328 Amifostine trihydrate 97% 1g $266 2021-12-16 Buy
Arctom HY-B0639A Amifostine trihydrate 99.95% 5g $437 2026-05-26 Buy

Properties

storage temp. :2-8°C
solubility :PBS (pH 7.2): 5 mg/ml
form :powder
pka :pKa1 <2.0; pKa2 4.2; pKa3 9.0; pKa4 11.7(at 25℃)
color :White to off-white
InChI :InChI=1S/C5H15N2O3PS.H2O/c6-2-1-3-7-4-5-12-11(8,9)10;/h7H,1-6H2,(H2,8,9,10);1H2
InChIKey :JKOQGQFVAUAYPM-UHFFFAOYSA-N
SMILES :S(P(O)(O)=O)CCNCCCN.O
CAS DataBase Reference :112901-68-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Amifostine is a prodrug that through dephosphorylation by alkaline phosphatase is converted to an active thiol, WR 1065 that has free radical scavenging, DNA protective, and hypoxia inducing activities. Because of the differential expression of alkaline phosphatase in normal versus neoplastic tissues, the cytoprotection conferred by amifostine is selective, enabling as much as 100-fold greater accumulation of WR 1065 in normal tissues than in tumor cells. Amifostine has been used to reduce toxicity in normal tissues exposed to radiation or chemotherapeutic agents. In mouse fibroblasts and various cancer cells, amifostine (IC50 = 4 mM) has been shown to activate p53 protein, to induce the expression of the cyclin-dependent kinase inhibitor p21, and to arrest cells at the G1/S transition through a p53-dependent mechanism.

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