4-OXO-1,4-DIHYDRO-[1,10]PHENANTHROLINE-3-CARBOXYLIC ACID
![4-OXO-1,4-DIHYDRO-[1,10]PHENANTHROLINE-3-CARBOXYLIC ACID price.](/CAS/GIF/331830-20-7.gif)
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- $32 - $1192.75
- Product name: 4-OXO-1,4-DIHYDRO-[1,10]PHENANTHROLINE-3-CARBOXYLIC ACID
- CAS: 331830-20-7
- MF: C13H8N2O3
- MW: 240.21
- EINECS:
- MDL Number:MFCD07357380
- Synonyms:4-OXO-1,4-DIHYDRO-[1,10]PHENANTHROLINE-3-CARBOXYLIC ACID;TVBAVFFTADCWKG-UHFFFAOYSA-N;4-DPCA;HIF-PH,HIF/HIF Prolyl-Hydroxylase,HIF-1α,HIFs,FIH,P4HA1,P4HA2,1,4DPCA,healing,Inhibitor,Hypoxia-inducible factors,1,4 DPCA,wound,inhibit,1,4-DPCA,P4HA3;1,10-Phenanthroline-3-carboxylic acid, 4,4a-dihydro-4-oxo-;4-Oxo-4,4a-dihydro-1,10-phenanthroline-3-carboxylic acid;1,4-DPCA, 10 mM in DMSO;1,4-DPCA
37 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Cayman Chemical
- ChemScene
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250MG
- Manufactureraablocks
- Product numberAA00C0T1
- Product description1,4-DPCA 98%
- Packaging25mg
- Price$83
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0T1
- Product description1,4-DPCA 98%
- Packaging10mg
- Price$51
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0T1
- Product description1,4-DPCA 98%
- Packaging5mg
- Price$32
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227158
- Product description1,4-DPCA 97.00%
- Packaging25MG
- Price$185
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227158
- Product description1,4-DPCA 97.00%
- Packaging100MG
- Price$475
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227158
- Product description1,4-DPCA 97.00%
- Packaging250MG
- Price$950
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1126AH
- Product description1,4-DPCA
- Packaging50mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005687
- Product description4-OXO-1,4-DIHYDRO-1,10-PHENANTHROLINE-3-CARBOXYLIC ACID 95.00%
- Packaging250MG
- Price$1192.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005687
- Product description4-OXO-1,4-DIHYDRO-1,10-PHENANTHROLINE-3-CARBOXYLIC ACID 95.00%
- Packaging5MG
- Price$495.76
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3302
- Product description1,4-DPCA
- Packaging25mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3302
- Product description1,4-DPCA
- Packaging25mg
- Price$371
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3302
- Product description1,4-DPCA
- Packaging50mg
- Price$379
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3302
- Product description1,4-DPCA
- Packaging10mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3302
- Product description1,4-DPCA
- Packaging10mg
- Price$189
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3302
- Product description1,4-DPCA
- Packaging50mg
- Price$649
- Updated2026-05-06
- Buy
- ManufacturerAvaChem
- Product number6002
- Product description1,4-DPCA 98%
- Packaging25mg
- Price$160
- Updated2026-05-22
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C0T1 | 1,4-DPCA 98% | 25mg | $83 | 2026-05-28 | Buy |
| aablocks | AA00C0T1 | 1,4-DPCA 98% | 10mg | $51 | 2026-05-28 | Buy |
| aablocks | AA00C0T1 | 1,4-DPCA 98% | 5mg | $32 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227158 | 1,4-DPCA 97.00% | 25MG | $185 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227158 | 1,4-DPCA 97.00% | 100MG | $475 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227158 | 1,4-DPCA 97.00% | 250MG | $950 | 2026-05-27 | Buy |
| AK Scientific | 1126AH | 1,4-DPCA | 50mg | $468 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005687 | 4-OXO-1,4-DIHYDRO-1,10-PHENANTHROLINE-3-CARBOXYLIC ACID 95.00% | 250MG | $1192.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005687 | 4-OXO-1,4-DIHYDRO-1,10-PHENANTHROLINE-3-CARBOXYLIC ACID 95.00% | 5MG | $495.76 | 2021-12-16 | Buy |
| ApexBio Technology | C3302 | 1,4-DPCA | 25mg | $216 | 2021-12-16 | Buy |
| ApexBio Technology | C3302 | 1,4-DPCA | 25mg | $371 | 2026-05-06 | Buy |
| ApexBio Technology | C3302 | 1,4-DPCA | 50mg | $379 | 2021-12-16 | Buy |
| ApexBio Technology | C3302 | 1,4-DPCA | 10mg | $97 | 2021-12-16 | Buy |
| ApexBio Technology | C3302 | 1,4-DPCA | 10mg | $189 | 2026-05-06 | Buy |
| ApexBio Technology | C3302 | 1,4-DPCA | 50mg | $649 | 2026-05-06 | Buy |
| AvaChem | 6002 | 1,4-DPCA 98% | 25mg | $160 | 2026-05-22 | Buy |
Properties
Boiling point :419.5±45.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 15 mg/ml with warming).
form :Tan solid.
pka :2.55±0.20(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 15 mg/ml with warming).
form :Tan solid.
pka :2.55±0.20(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Safety Information
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Description
The pro-angiogenic factor HIF-1α is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH). Inhibitors of prolyl 4-hydroxylase are potentially useful in controlling excess collagen deposition in pathological fibrosis. 1,4-DPCA is a competitive inhibitor of prolyl 4-hydroxylase in embryonic chick tendon cells and of collagen hydroxylation in human foreskin fibroblasts with an IC50 value of 3.6 and 2.4 μM, respectively. β-oxocarboxylic acids such as 1,4-DPCA have also been found to inhibit the asparaginyl-hydroxylase, factor inhibiting HIF (FIH), with an IC50 value of 60 μM.More related product prices
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