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ChemicalBook >> CAS DataBase List >> (-)-BETA-HYDRASTINE

(-)-BETA-HYDRASTINE

(-)-BETA-HYDRASTINE price.
  • $29 - $1635
  • Product name: (-)-BETA-HYDRASTINE
  • CAS: 118-08-1
  • MF: C21H21NO6
  • MW: 383.39
  • EINECS:204-233-0
  • MDL Number:MFCD00152561
  • Synonyms:HYDRASTINE, (-)-B-(P) (AHP Verified);HYDRASTINE, (-)-B-(P);Hydrastine (base and/or unspecified salts);(1R,9S)-(-)-β-Hydrastine;(3R)-6,7-Dimethoxy-3-[[(1R)-1,2,3,4-tetrahydro-2-methyl-6,7-(methylenedioxy)isoquinoline]-1-yl]isobenzofuran-1(3H)-one;[R,(-)]-6,7-Dimethoxy-3-[[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinoline]-5-yl]isobenzofuran-1(3H)-one;(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone;[S,(-)]-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one
54 prices
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  • aablocks
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
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  • 1mlx10mM(inDMSO)
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  • 5g
  • Manufactureraablocks
  • Product numberAA008TJB
  • Product description(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
  • Packaging10mg
  • Price$99
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJB
  • Product description(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
  • Packaging25mg
  • Price$150
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJB
  • Product description(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
  • Packaging5mg
  • Price$62
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TJB
  • Product description(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
  • Packaging2mg
  • Price$46
  • Updated2026-05-28
  • Buy
  • ManufacturerAHH
  • Product numberMT-52735
  • Product descriptionHydrastine 98%
  • Packaging5g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-52735
  • Product descriptionHydrastine 97%
  • Packaging5g
  • Price$230
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-52735
  • Product descriptionHydrastine 97%
  • Packaging5g
  • Price$230
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product number6606AF
  • Product descriptionHydrastine
  • Packaging10mg
  • Price$241
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0001683
  • Product descriptionHYDRASTINE 98.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSLK-E2484
  • Product descriptionHydrastine 99.48%
  • Packaging5mg
  • Price$304
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberSLK-E2484
  • Product descriptionHydrastine 99.48%
  • Packaging5mg
  • Price$304
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberAS348789
  • Product descriptionHydrastine
  • Packaging10mg
  • Price$378
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAB2874
  • Product descriptionHydrastine 98%(HPLC)
  • Packaging20mg
  • Price$235
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberSLK-E2484
  • Product descriptionHydrastine 99.48%
  • Packaging1mg
  • Price$102
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberSLK-E2484
  • Product descriptionHydrastine 99.48%
  • Packaging1mg
  • Price$102
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0927
  • Product descriptionHydrastine 99.57%
  • Packaging10mg
  • Price$114
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008TJB (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone 10mg $99 2026-05-28 Buy
aablocks AA008TJB (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone 25mg $150 2026-05-28 Buy
aablocks AA008TJB (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone 5mg $62 2026-05-28 Buy
aablocks AA008TJB (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone 2mg $46 2026-05-28 Buy
AHH MT-52735 Hydrastine 98% 5g $230 2021-12-16 Buy
AHH MT-52735 Hydrastine 97% 5g $230 2026-05-25 Buy
AHH MT-52735 Hydrastine 97% 5g $230 2026-05-26 Buy
AK Scientific 6606AF Hydrastine 10mg $241 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001683 HYDRASTINE 98.00% 10MG $716.1 2021-12-16 Buy
Arctom SLK-E2484 Hydrastine 99.48% 5mg $304 2026-05-25 Buy
Arctom SLK-E2484 Hydrastine 99.48% 5mg $304 2026-05-26 Buy
Arctom AS348789 Hydrastine 10mg $378 2021-12-16 Buy
Arctom AB2874 Hydrastine 98%(HPLC) 20mg $235 2026-05-26 Buy
Arctom SLK-E2484 Hydrastine 99.48% 1mg $102 2026-05-25 Buy
Arctom SLK-E2484 Hydrastine 99.48% 1mg $102 2026-05-26 Buy
Arctom HY-B0927 Hydrastine 99.57% 10mg $114 2026-05-26 Buy

Properties

Melting point :132℃
alpha :D20 -50° (c = 0.3 in abs alc)
Boiling point :510.32°C (rough estimate)
Density :1.339±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5614 (estimate)
storage temp. :−20°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :7.8(at 25℃)
color :White to light yellow
Water Solubility :30mg/L(20 ºC)
CAS DataBase Reference :118-08-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

(1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 μM in PC12 cells) by inhibiting tyrosine hydroxylase activity. It inhibits dopamine release with an IC50 value of 66.5 μM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.

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