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ChemicalBook >> CAS DataBase List >> Bufalin

Bufalin

Bufalin price.
  • $31 - $2900
  • Product name: Bufalin
  • CAS: 465-21-4
  • MF: C24H34O4
  • MW: 386.53
  • EINECS:
  • MDL Number:MFCD30207876
  • Synonyms:22-dienolide,3,14-dihydroxy-,(3-beta,5-beta)-bufa-2 ;Bufalin, >=98%;22-dienolide,3-beta,14-dihydroxy-5-beta-bufa-2 ;BUFA-20,22-DIENOLIDE, 3,14-DIHYDROXY-, (3B,5B)-;(3BETA,5BETA)-3,14-DIHYDROXYBUFA-20,22-DIENOLIDE;3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE;3BETA,14-DIHYDROXY-5BETA,20[22]-BUFADIENOLIDE;5BETA,20[22]-BUFADIENOLIDE-3BETA,14-DIOL
92 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 250mg
  • 10mM*1mLinDMSO(Solution)
  • 2mg
  • 500mg
  • 10mM*1mLinDMSO
  • 1g
  • 1000mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 5mg
  • 10mg
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  • 100MG
  • Manufactureraablocks
  • Product numberAA00I8HZ
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98%
  • Packaging1mg
  • Price$31
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I8HZ
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98%
  • Packaging5mg
  • Price$38
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8HZ
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98%
  • Packaging10mg
  • Price$53
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8HZ
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98
  • Packaging25mg
  • Price$127
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I8HZ
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98
  • Packaging50mg
  • Price$178
  • Updated2026-05-29
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  • ManufacturerACHEMBLOCK
  • Product numberU106021
  • Product descriptionBufalin 98.00%
  • Packaging100MG
  • Price$390
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberU106021
  • Product descriptionBufalin 98.00%
  • Packaging50MG
  • Price$235
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0533-M050
  • Product descriptionBufalin ≥98%(HPLC)
  • Packaging50mg
  • Price$240
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0533-M010
  • Product descriptionBufalin ≥98%(HPLC)
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0533-M010
  • Product descriptionBufalin ≥98%(HPLC)
  • Packaging10mg
  • Price$60
  • Updated2026-05-06
  • Buy
  • ManufacturerAmbeed
  • Product numberA206803
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
  • Packaging1mg
  • Price$44
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA206803
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
  • Packaging10mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA206803
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
  • Packaging5mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA206803
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
  • Packaging100mg
  • Price$554
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA206803
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
  • Packaging25mg
  • Price$251
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA206803
  • Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
  • Packaging50mg
  • Price$373
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I8HZ 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98% 1mg $31 2026-05-29 Buy
aablocks AA00I8HZ 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98% 5mg $38 2026-05-29 Buy
aablocks AA00I8HZ 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98% 10mg $53 2026-05-29 Buy
aablocks AA00I8HZ 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98 25mg $127 2026-05-29 Buy
aablocks AA00I8HZ 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98 50mg $178 2026-05-29 Buy
ACHEMBLOCK U106021 Bufalin 98.00% 100MG $390 2026-05-27 Buy
ACHEMBLOCK U106021 Bufalin 98.00% 50MG $235 2026-05-27 Buy
Adipogen Life Sciences AG-CN2-0533-M050 Bufalin ≥98%(HPLC) 50mg $240 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0533-M010 Bufalin ≥98%(HPLC) 10mg $60 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0533-M010 Bufalin ≥98%(HPLC) 10mg $60 2026-05-06 Buy
Ambeed A206803 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% 1mg $44 2021-12-16 Buy
Ambeed A206803 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% 10mg $148 2021-12-16 Buy
Ambeed A206803 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% 5mg $99 2021-12-16 Buy
Ambeed A206803 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% 100mg $554 2021-12-16 Buy
Ambeed A206803 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% 25mg $251 2021-12-16 Buy
Ambeed A206803 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% 50mg $373 2021-12-16 Buy

Properties

Melting point :242-243°
alpha :D -20°
Boiling point :556.6±50.0 °C(Predicted)
Density :1.226±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO:36.0(Max Conc. mg/mL);93.14(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);64.68(Max Conc. mM)
Ethanol:27.5(Max Conc. mg/mL);71.15(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.78(Max Conc. mM) form :White to off-white solid
pka :15.01±0.70(Predicted)
color :White to off-white
Major Application :food and beverages
InChIKey :QEEBRPGZBVVINN-ONGIWDLKSA-N
SMILES :O[C@]12CC[C@H](C3=COC(C=C3)=O)[C@]1(CC[C@]1([H])[C@]3(CC[C@@H](C[C@@]3([H])CC[C@@]21[H])O)C)C

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Bufalin is a cardiotonic steroid first isolated from toad venom and used in traditional Asian medicine. It inhibits the Na+/K+-ATPase transporter (Kds = 42, 45, and 40 nM for the α1, α2, and α3 subunits, respectively). Intravenously administered bufalin is cleared rapidly, with a plasma half-life of 25 minutes in dogs and rats. Bufalin inhibits steroid receptor coactivator 1 (SRC-1) and SRC-3 at doses as low as 5 nM, promotes the degradation of SRC-3 protein, and inhibits cancer cell growth both in vitro and in vivo. It can also impact the action and expression of several other proteins and kinases as well as induce apoptosis in various cancer cells.

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