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ChemicalBook >> CAS DataBase List >> Irinotecan hydrochloride

Irinotecan hydrochloride

Irinotecan hydrochloride price.
  • $25 - $3109.75
  • Product name: Irinotecan hydrochloride
  • CAS: 100286-90-6
  • MF: C33H39ClN4O6
  • MW: 623.15
  • EINECS:600-054-0
  • MDL Number:MFCD01862255
  • Synonyms:7-ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycamptothecinhydrochlor ;Irinotecan hydrochloride (S)-[1,4'-Bipiperidine]-1'-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride;(S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3?,4?:6,7]indolizino[1,2-b]quinolin-9-yl ester monohydrochloride trihydrate;Camptothecin 11;U 101440E;(S)-[1,4'-Bipiperidine]-1'-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride;[1,4’-Bipiperidine]-1’-carboxylic Acid (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-9-yl Ester Hydrochloride Trihydrate;CTP-11
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  • Manufactureraablocks
  • Product numberAA00H94H
  • Product description(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 98%
  • Packaging50mg
  • Price$29
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00H94H
  • Product description(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 98%
  • Packaging100mg
  • Price$48
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00H94H
  • Product description(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95%
  • Packaging250mg
  • Price$50
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00H94H
  • Product description(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95%
  • Packaging1g
  • Price$96
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00H94H
  • Product description(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95%
  • Packaging5g
  • Price$240
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00H94H
  • Product description(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95%
  • Packaging25g
  • Price$1029
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberX212280
  • Product descriptionIrinotecan hydrochloride 97%
  • Packaging5G
  • Price$575
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberX212280
  • Product descriptionIrinotecan hydrochloride 97%
  • Packaging1G
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  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberJ53069
  • Product descriptionIrinotecan hydrochloride
  • Packaging5g
  • Price$2128
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging50mg
  • Price$100
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging100mg
  • Price$150
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging200mg
  • Price$216
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging500mg
  • Price$430
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging1g
  • Price$836
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging5g
  • Price$2924
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH851
  • Product descriptionIrinotecan hydrochloride 98%(HPLC)
  • Packaging25mg
  • Price$62
  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00H94H (19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 98% 50mg $29 2026-05-28 Buy
aablocks AA00H94H (19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 98% 100mg $48 2026-05-28 Buy
aablocks AA00H94H (19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95% 250mg $50 2026-05-28 Buy
aablocks AA00H94H (19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95% 1g $96 2026-05-28 Buy
aablocks AA00H94H (19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95% 5g $240 2026-05-28 Buy
aablocks AA00H94H (19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride 95% 25g $1029 2026-05-28 Buy
ACHEMBLOCK X212280 Irinotecan hydrochloride 97% 5G $575 2026-05-27 Buy
ACHEMBLOCK X212280 Irinotecan hydrochloride 97% 1G $165 2026-05-27 Buy
AK Scientific J53069 Irinotecan hydrochloride 5g $2128 2021-12-16 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 50mg $100 2026-06-04 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 100mg $150 2026-06-04 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 200mg $216 2026-06-04 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 500mg $430 2026-06-04 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 1g $836 2026-06-04 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 5g $2924 2026-06-04 Buy
AK Scientific H851 Irinotecan hydrochloride 98%(HPLC) 25mg $62 2026-06-04 Buy

Properties

Melting point :250-256°C (dec.)
Boiling point :257 °C
refractive index :67.7 ° (C=1, H2O)
storage temp. :2-8°C
solubility :Soluble in DMSO or DMF at approximately 20mg/ml. Sparingly soluble in aqueous buffers. /n
form :Yellow powder
color :White to yellow
biological source :plant (Fructus camptothecae)
Water Solubility :Soluble in DMSO at 100mg/ml. Soluble in water at 25mg/ml with warming
Merck :5091
InChIKey :GURKHSYORGJETM-GCUJQDEHNA-N
SMILES :C(C1C2=CC(OC(N3CCC(N4CCCCC4)CC3)=O)=CC=C2N=C2C3=CC4[C@@](C(=O)OCC=4C(=O)N3CC=12)(O)CC)C.Cl |&1:28,r|
CAS DataBase Reference :100286-90-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

Irinotecan, a derivative of the alkaloid camptothecin , functions as a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin, a potent inhibitor of DNA topoisomerase I. Its action is terminated by glucuronidation by UDP glucuronosyl transferase 1A1. Irinotecan demonstrates a broad spectrum of antitumor activity against metastatic colorectal cancer, small cell lung cancer, and several other solid tumors and has proven useful in radiation treatment of tumors by sensitizing tissue to radiation damage.

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