JNK-IN-8
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- $15 - $2400
- Product name: JNK-IN-8
- CAS: 1410880-22-6
- MF: C29H29N7O2
- MW: 507.59
- EINECS:
- MDL Number:MFCD22124890
- Synonyms:JNK-IN-8;(E)-3-(4-(diMethylaMino)but-2-enaMido)-N-(3-Methyl-4-(4-(pyridin-3-yl)pyriMidin-2-ylaMino)phenyl)benzaMide;3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide;JNK Inhibitor XVI;Benzamide, 3-[[4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-;3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide JNK-IN-8;JNK-IN-8 Only for R&D;JNK-IN-8 USP/EP/BP
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 2x5mg
- 10mM*1mLinDMSO(Solution)
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 200mg
- 10mM*1mLinDMSO
- 2x25mg
- 250mg
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 1G
- Manufactureraablocks
- Product numberAA001FSV
- Product descriptionJNK-IN-8 98%
- Packaging1mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001FSV
- Product descriptionJNK-IN-8 98%
- Packaging2mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001FSV
- Product descriptionJNK-IN-8 98%
- Packaging5mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001FSV
- Product descriptionJNK-IN-8 98%
- Packaging10mg
- Price$34
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001FSV
- Product descriptionJNK-IN-8 98%
- Packaging25mg
- Price$54
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001FSV
- Product descriptionJNK-IN-8 98%
- Packaging50mg
- Price$92
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10218
- Product descriptionJNK-IN-8 98%
- Packaging100MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10218
- Product descriptionJNK-IN-8 98%
- Packaging25MG
- Price$60
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10218
- Product descriptionJNK-IN-8 98%
- Packaging1G
- Price$750
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY1469
- Product descriptionJNK-IN-8
- Packaging25mg
- Price$667
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3520
- Product descriptionJNK-IN-8
- Packaging50mg
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3520
- Product descriptionJNK-IN-8
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3520
- Product descriptionJNK-IN-8
- Packaging50mg
- Price$440
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3520
- Product descriptionJNK-IN-8
- Packaging5mg
- Price$76
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3520
- Product descriptionJNK-IN-8
- Packaging10mM(in 1mL DMSO)
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3520
- Product descriptionJNK-IN-8
- Packaging10mM(in1mLDMSO)
- Price$88
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001FSV | JNK-IN-8 98% | 1mg | $15 | 2026-05-28 | Buy |
| aablocks | AA001FSV | JNK-IN-8 98% | 2mg | $18 | 2026-05-28 | Buy |
| aablocks | AA001FSV | JNK-IN-8 98% | 5mg | $24 | 2026-05-28 | Buy |
| aablocks | AA001FSV | JNK-IN-8 98% | 10mg | $34 | 2026-05-28 | Buy |
| aablocks | AA001FSV | JNK-IN-8 98% | 25mg | $54 | 2026-05-28 | Buy |
| aablocks | AA001FSV | JNK-IN-8 98% | 50mg | $92 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10218 | JNK-IN-8 98% | 100MG | $150 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10218 | JNK-IN-8 98% | 25MG | $60 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10218 | JNK-IN-8 98% | 1G | $750 | 2026-05-27 | Buy |
| AK Scientific | Y1469 | JNK-IN-8 | 25mg | $667 | 2021-12-16 | Buy |
| ApexBio Technology | A3520 | JNK-IN-8 | 50mg | $540 | 2021-12-16 | Buy |
| ApexBio Technology | A3520 | JNK-IN-8 | 10mg | $180 | 2021-12-16 | Buy |
| ApexBio Technology | A3520 | JNK-IN-8 | 50mg | $440 | 2026-05-06 | Buy |
| ApexBio Technology | A3520 | JNK-IN-8 | 5mg | $76 | 2026-05-06 | Buy |
| ApexBio Technology | A3520 | JNK-IN-8 | 10mM(in 1mL DMSO) | $152 | 2021-12-16 | Buy |
| ApexBio Technology | A3520 | JNK-IN-8 | 10mM(in1mLDMSO) | $88 | 2026-05-06 | Buy |
Properties
Density :1.283±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥25.4 mg/mL in DMSO; insoluble in H2O; ≥9.24 mg/mL in EtOH with gentle warming and ultrasonic
pka :13.34±0.70(Predicted)
form :powder
color :white to beige
InChIKey :GJFCSAPFHAXMSF-UHFFFAOYSA-N
SMILES :O=C(C1=CC(NC(C=CCN(C)C)=O)=CC=C1)NC(C=C2C)=CC=C2NC3=NC=CC(C4=CC=CN=C4)=N3
storage temp. :2-8°C
solubility :≥25.4 mg/mL in DMSO; insoluble in H2O; ≥9.24 mg/mL in EtOH with gentle warming and ultrasonic
pka :13.34±0.70(Predicted)
form :powder
color :white to beige
InChIKey :GJFCSAPFHAXMSF-UHFFFAOYSA-N
SMILES :O=C(C1=CC(NC(C=CCN(C)C)=O)=CC=C1)NC(C=C2C)=CC=C2NC3=NC=CC(C4=CC=CN=C4)=N3
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. JNK inhibitor XVI is a selective, irreversible JNK inhibitor (IC50s = 4.67, 18.7, and 0.98 nM for JNK1, 2, and 3, respectively) that prevents phosphorylation of c-Jun in A375 and HeLa cells with EC50 values of 338 and 486 nM, respectively. It has been shown to inhibit JNK kinase activity by a mechanism that depends on covalent modification of cysteine116 in the ATP-binding motif. This compound has been used to explore the role of JNK in mediating cancer cell death.More related product prices
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