LAZABEMIDE
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- $33 - $2820
- Product name: LAZABEMIDE
- CAS: 103878-84-8
- MF: C8H10ClN3O
- MW: 199.64
- EINECS:
- MDL Number:MFCD00865419
- Synonyms:LAZABEMIDE;LAZABEMIDE HYDROCHLORIDE;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide;Ro-19-6327;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-;Ro 19-6327/000;Lazabemide hydrate;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate
42 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AHH
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 50
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA008SQE
- Product descriptionN-(2-Aminoethyl)-5-chloropicolinamide ≥95%
- Packaging5mg
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQE
- Product descriptionN-(2-Aminoethyl)-5-chloropicolinamide ≥95%
- Packaging10mg
- Price$69
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQE
- Product descriptionN-(2-Aminoethyl)-5-chloropicolinamide ≥98%
- Packaging25mg
- Price$160
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQE
- Product descriptionN-(2-Aminoethyl)-5-chloropicolinamide ≥98%
- Packaging50mg
- Price$280
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQE
- Product descriptionN-(2-Aminoethyl)-5-chloropicolinamide ≥98%
- Packaging100mg
- Price$480
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008SQE
- Product descriptionN-(2-Aminoethyl)-5-chloropicolinamide ≥98%
- Packaging250mg
- Price$960
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberS89171
- Product descriptionLAZABEMIDE 95%
- Packaging1G
- Price$2820
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS89171
- Product descriptionLAZABEMIDE 95%
- Packaging1G
- Price$2820
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS89171
- Product descriptionLAZABEMIDE 95%
- Packaging250MG
- Price$940
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS89171
- Product descriptionLAZABEMIDE 95%
- Packaging250MG
- Price$940
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS89171
- Product descriptionLAZABEMIDE 95%
- Packaging100MG
- Price$470
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS89171
- Product descriptionLAZABEMIDE 95%
- Packaging100MG
- Price$470
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberMT-53148
- Product descriptionLazabemide 98%
- Packaging1g
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-53148
- Product descriptionLazabemide 97%
- Packaging1g
- Price$310
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-53148
- Product descriptionLazabemide 97%
- Packaging1g
- Price$310
- Updated2026-05-26
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004993
- Product descriptionLAZABEMIDE 95.00%
- Packaging5MG
- Price$144.1
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008SQE | N-(2-Aminoethyl)-5-chloropicolinamide ≥95% | 5mg | $37 | 2026-05-28 | Buy |
| aablocks | AA008SQE | N-(2-Aminoethyl)-5-chloropicolinamide ≥95% | 10mg | $69 | 2026-05-28 | Buy |
| aablocks | AA008SQE | N-(2-Aminoethyl)-5-chloropicolinamide ≥98% | 25mg | $160 | 2026-05-28 | Buy |
| aablocks | AA008SQE | N-(2-Aminoethyl)-5-chloropicolinamide ≥98% | 50mg | $280 | 2026-05-28 | Buy |
| aablocks | AA008SQE | N-(2-Aminoethyl)-5-chloropicolinamide ≥98% | 100mg | $480 | 2026-05-28 | Buy |
| aablocks | AA008SQE | N-(2-Aminoethyl)-5-chloropicolinamide ≥98% | 250mg | $960 | 2026-05-28 | Buy |
| ACHEMBLOCK | S89171 | LAZABEMIDE 95% | 1G | $2820 | 2026-05-25 | Buy |
| ACHEMBLOCK | S89171 | LAZABEMIDE 95% | 1G | $2820 | 2026-05-27 | Buy |
| ACHEMBLOCK | S89171 | LAZABEMIDE 95% | 250MG | $940 | 2026-05-25 | Buy |
| ACHEMBLOCK | S89171 | LAZABEMIDE 95% | 250MG | $940 | 2026-05-27 | Buy |
| ACHEMBLOCK | S89171 | LAZABEMIDE 95% | 100MG | $470 | 2026-05-25 | Buy |
| ACHEMBLOCK | S89171 | LAZABEMIDE 95% | 100MG | $470 | 2026-05-27 | Buy |
| AHH | MT-53148 | Lazabemide 98% | 1g | $310 | 2021-12-16 | Buy |
| AHH | MT-53148 | Lazabemide 97% | 1g | $310 | 2026-05-25 | Buy |
| AHH | MT-53148 | Lazabemide 97% | 1g | $310 | 2026-05-26 | Buy |
| American Custom Chemicals Corporation | INB0004993 | LAZABEMIDE 95.00% | 5MG | $144.1 | 2021-12-16 | Buy |
Properties
Boiling point :397.4±37.0 °C(Predicted)
Density :1.286±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥22mg/mL
pka :12.90±0.46(Predicted)
form :powder
color :white to tan
InChI :1S/C8H10ClN3O.H2O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10;/h1-2,5H,3-4,10H2,(H,11,13);1H2
InChIKey :JYWYNPKXSLPWGV-UHFFFAOYSA-N
SMILES :O.NCCNC(=O)c1ccc(Cl)cn1
Density :1.286±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥22mg/mL
pka :12.90±0.46(Predicted)
form :powder
color :white to tan
InChI :1S/C8H10ClN3O.H2O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10;/h1-2,5H,3-4,10H2,(H,11,13);1H2
InChIKey :JYWYNPKXSLPWGV-UHFFFAOYSA-N
SMILES :O.NCCNC(=O)c1ccc(Cl)cn1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Monoamine oxidases, MAO-A and MAO-B, regulate the intracellular concentrations of biogenic monoamines such as 5-hydroxytryptamine and dopamine via oxidative deamination. Inhibitors of MAO-A are widely used for the therapy of affective disorders, whereas MAO-B inhibitors have clinical efficacy in the treatment of Parkinson’s disease. Lazabemide is a reversible inhibitor of monoamine oxidase B (MAO-B) with IC50 values of 0.48 and 1.5 μM measured in platelets of human subjects ages 19-36 and 60-78, respectively. It is structurally similar to the MAO-B preferential substrate phenylethylamine and can be oxidized by MAO-B, forming tightly, but reversibly, bound adducts with the active site of the enzyme. The selectivity of lazabemide for MAO-B inhibition has been demonstrated in both in vitro and ex vivo conditions and it was evaluated in clinical trials for possible neuroprotective actions in the treatment of Parkinson’s disease.Related product price
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