LY-2562175
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- $46 - $4327
- Product name: LY-2562175
- CAS: 1103500-20-4
- MF: C28H27Cl2N3O4
- MW: 540.44
- EINECS:-0
- MDL Number:MFCD30738721
- Synonyms:LY-2562175;CS-2847;1H-Indole-3-carboxylic acid, 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]-1-piperidinyl]-1-methyl-;LY 2562175,NR1H4,Inhibitor,LY-2562175,Autophagy,LY2562175,inhibit,FXR;6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid;LY2562175, 10 mM in DMSO;TERN-101
51 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA01EOD3
- Product descriptionLY2562175 99%
- Packaging5mg
- Price$135
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EOD3
- Product descriptionLY2562175 99%
- Packaging1mg
- Price$46
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EOD3
- Product descriptionLY2562175 99%
- Packaging10mg
- Price$229
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EOD3
- Product descriptionLY2562175 99%
- Packaging25mg
- Price$390
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EOD3
- Product descriptionLY2562175 99
- Packaging100mg
- Price$1340
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberU140712
- Product description6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid 98%
- Packaging25MG
- Price$930
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU140712
- Product description6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid 98%
- Packaging5MG
- Price$280
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU140712
- Product description6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid 98%
- Packaging100MG
- Price$1980
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3150DC
- Product description6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylicacid
- Packaging10mg
- Price$1342
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging50mg
- Price$1403
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$328
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging10mM*1mLinDMSO(Solution)
- Price$328
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging10mg
- Price$447
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging5mg
- Price$276
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging100mg
- Price$1881
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103704
- Product descriptionLY2562175 99.49%
- Packaging25mg
- Price$893
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EOD3 | LY2562175 99% | 5mg | $135 | 2026-05-30 | Buy |
| aablocks | AA01EOD3 | LY2562175 99% | 1mg | $46 | 2026-05-30 | Buy |
| aablocks | AA01EOD3 | LY2562175 99% | 10mg | $229 | 2026-05-30 | Buy |
| aablocks | AA01EOD3 | LY2562175 99% | 25mg | $390 | 2026-05-30 | Buy |
| aablocks | AA01EOD3 | LY2562175 99 | 100mg | $1340 | 2026-05-30 | Buy |
| ACHEMBLOCK | U140712 | 6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid 98% | 25MG | $930 | 2026-05-27 | Buy |
| ACHEMBLOCK | U140712 | 6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid 98% | 5MG | $280 | 2026-05-27 | Buy |
| ACHEMBLOCK | U140712 | 6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid 98% | 100MG | $1980 | 2026-05-27 | Buy |
| AK Scientific | 3150DC | 6-[4-[[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylicacid | 10mg | $1342 | 2021-12-16 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 50mg | $1403 | 2026-05-26 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 10mM*1mLinDMSO(Solid+Solvent) | $328 | 2026-05-26 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 10mM*1mLinDMSO(Solution) | $328 | 2026-05-26 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 10mg | $447 | 2026-05-26 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 5mg | $276 | 2026-05-26 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 100mg | $1881 | 2026-05-26 | Buy |
| Arctom | HY-103704 | LY2562175 99.49% | 25mg | $893 | 2026-05-26 | Buy |
Properties
Boiling point :740.1±60.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
pka :3.43±0.10(Predicted)
color :White to light yellow
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
pka :3.43±0.10(Predicted)
color :White to light yellow
Safety Information
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Description
LY2562175 is a farnesoid X receptor (FXR) agonist (EC50 = 193 nM in a reporter assay). It is selective for FXR over the glucocorticoid, androgen, mineralocorticoid, and progesterone receptors in HEK293 cells overexpressing the human receptors (EC50s = >10 μM for all in a radioligand binding assay). LY2562175 increases the interaction between FXR and steroid receptor coactivator 1 (SRC-1) with an EC50 value of 121 nM in a cell-free assay. It reduces plasma triglyceride and total cholesterol levels in LDL receptor-null mice (ED50s = 3.4 and 2 mg/kg, respectively). LY2562175 also decreases plasma LDL and increases HDL levels in Zucker diabetic fatty (ZDF) rats when administered at doses of 3, 10, and 30 mg/kg for nine days.Related product price
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