Lafutidine
|
- $6 - $2425.5
- Product name: Lafutidine
- CAS: 118288-08-7
- MF: C22H29N3O4S
- MW: 431.55
- EINECS:601-513-8
- MDL Number:MFCD00867520
- Synonyms:n-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide;2-((Furan-2-ylMethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylMethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetaMide;(Z)-2-((Furan-2-ylMethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylMethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetaMide;Adefovir Dipivioxil;(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl);(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-;LAFUTIDINE(SUBJECTTOPATENTFREE);118288-08-07
68 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 25mg
- 10mM(in1mLDMSO)
- 10mg
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 250.00mg
- 250mg
- 0.25g
- 1g
- 1.00g
- 5g
- 25G
- 100G
- 10 mg
- 50 mg
- Manufactureraablocks
- Product numberAA00HEDC
- Product descriptionLafutidine 99%
- Packaging250mg
- Price$9
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00HEDC
- Product descriptionLafutidine 99%
- Packaging1g
- Price$23
- Updated2026-05-29
- Buy
- ManufacturerAccelPharmtech
- Product numberAT6292
- Product descriptionLafutidine 99.00%
- Packaging25G
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberAT6292
- Product descriptionLafutidine 99.00%
- Packaging100G
- Price$960
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberAT6292
- Product descriptionLafutidine 99.00%
- Packaging100G
- Price$960
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT6292
- Product descriptionLafutidine 99.00%
- Packaging25G
- Price$460
- Updated2026-05-21
- Buy
- ManufacturerAHH
- Product numberAPI-1731
- Product descriptionLafutidine 98%
- Packaging0.25g
- Price$620
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1731
- Product descriptionLafutidine 97%
- Packaging0.25g
- Price$620
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberH692
- Product descriptionLafutidine
- Packaging250mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA101474
- Product description(+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+%
- Packaging1g
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA101474
- Product description(+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+%
- Packaging250mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA101474
- Product description(+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+%
- Packaging5g
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003112
- Product descriptionLAFUTIDINE 95.00%
- Packaging1G
- Price$2425.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1575
- Product descriptionLafutidine
- Packaging50mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1575
- Product descriptionLafutidine
- Packaging50mg
- Price$108
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1575
- Product descriptionLafutidine
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00HEDC | Lafutidine 99% | 250mg | $9 | 2026-05-29 | Buy |
| aablocks | AA00HEDC | Lafutidine 99% | 1g | $23 | 2026-05-29 | Buy |
| AccelPharmtech | AT6292 | Lafutidine 99.00% | 25G | $460 | 2021-12-16 | Buy |
| AccelPharmtech | AT6292 | Lafutidine 99.00% | 100G | $960 | 2021-12-16 | Buy |
| AccelPharmtech | AT6292 | Lafutidine 99.00% | 100G | $960 | 2026-05-21 | Buy |
| AccelPharmtech | AT6292 | Lafutidine 99.00% | 25G | $460 | 2026-05-21 | Buy |
| AHH | API-1731 | Lafutidine 98% | 0.25g | $620 | 2021-12-16 | Buy |
| AHH | API-1731 | Lafutidine 97% | 0.25g | $620 | 2026-05-26 | Buy |
| AK Scientific | H692 | Lafutidine | 250mg | $72 | 2021-12-16 | Buy |
| Ambeed | A101474 | (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+% | 1g | $37 | 2021-12-16 | Buy |
| Ambeed | A101474 | (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+% | 250mg | $15 | 2021-12-16 | Buy |
| Ambeed | A101474 | (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+% | 5g | $129 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003112 | LAFUTIDINE 95.00% | 1G | $2425.5 | 2021-12-16 | Buy |
| ApexBio Technology | B1575 | Lafutidine | 50mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | B1575 | Lafutidine | 50mg | $108 | 2026-05-06 | Buy |
| ApexBio Technology | B1575 | Lafutidine | 10mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :92.7-94.9°
Boiling point :704.2±60.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
Water Solubility :Insoluble in water
solubility :DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM)
DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM)
Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM) form :powder to crystal
pka :13.13±0.46(Predicted)
color :White to Orange to Green
InChI :1S/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-
InChIKey :KMZQAVXSMUKBPD-DJWKRKHSSA-N
SMILES :C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)(=O)CS(CC1=CC=CO1)=O
CAS DataBase Reference :118288-08-7(CAS DataBase Reference)
Boiling point :704.2±60.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
Water Solubility :Insoluble in water
solubility :DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM)
DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM)
Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM) form :powder to crystal
pka :13.13±0.46(Predicted)
color :White to Orange to Green
InChI :1S/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-
InChIKey :KMZQAVXSMUKBPD-DJWKRKHSSA-N
SMILES :C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)(=O)CS(CC1=CC=CO1)=O
CAS DataBase Reference :118288-08-7(CAS DataBase Reference)
Safety Information
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Description
Lafutidine was launched in Japan for the treatment of gastritis, reflux oesophagitis and peptic ulcers. It can be prepared in eight steps from 4-(2-tetrahydropyranyloxy)-2(Z)-butenl- ol. Lafutidine is a potent and longer-acting H2 antagonist compared to other marketed compounds of its class such as cimetidine and famotidine. In contrast to other commercially available H2 antagonists, lafutidine also exerts a gastroprotective action probably via capsaicin-sensitive afferent nerves. It was clinically effective in the treatment of nonsteroidal antiinflammatory drug-induced ulcer in patients refractory to existing antiulcer agents.Related product price
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Omeprazole
$5-1880 -
Famotidine
$5-899 -
Ranitidine hydrochloride
$10-1600.83
Suppliers and manufacturers
Moxin Chemicals
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Jinan Shengqi pharmaceutical Co,Ltd
HubeiwidelychemicaltechnologyCo.,Ltd
Alchem Pharmtech,Inc.
Shanghai Yingrui Biopharma Co.,Ltd
CONIER CHEM AND PHARMA LIMITED
SIMAGCHEM CORP
Lafutidine Impurity
CAS:118288-08-7
