ML115
|
- $49 - $2237
- Product name: ML115
- CAS: 912798-42-6
- MF: C15H15ClN2O4
- MW: 322.7436
- EINECS:
- MDL Number:MFCD09782805
- Synonyms:ML115;ML115,ML-115;3-Isoxazolecarboxamide, N-(4-chloro-2,5-dimethoxyphenyl)-5-cyclopropyl-;N-(4-Chloro-2,5-dimethoxyphenyl)-5-cyclopropylisoxazole-3-carboxamide
29 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Cayman Chemical
- ChemScene
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 200mg
- Manufactureraablocks
- Product numberAA01E5P8
- Product descriptionML-115 99%
- Packaging5mg
- Price$89
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5P8
- Product descriptionML-115 99%
- Packaging10mg
- Price$133
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5P8
- Product descriptionML-115 99%
- Packaging25mg
- Price$253
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5P8
- Product descriptionML-115 99
- Packaging200mg
- Price$1364
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227984
- Product descriptionML115 97.00%
- Packaging25MG
- Price$795
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227984
- Product descriptionML115 97.00%
- Packaging100MG
- Price$1500
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227984
- Product descriptionML115 97.00%
- Packaging5MG
- Price$285
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5305
- Product descriptionML115
- Packaging10mg
- Price$362
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5305
- Product descriptionML115
- Packaging100mg
- Price$2237
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15178
- Product descriptionML-115 ≥98%
- Packaging5mg
- Price$392
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15178
- Product descriptionML115 ≥98%
- Packaging1mg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15178
- Product descriptionML-115 ≥98%
- Packaging1mg
- Price$102
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15178
- Product descriptionML115 ≥98%
- Packaging500μg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15178
- Product descriptionML-115 ≥98%
- Packaging500μg
- Price$54
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15178
- Product descriptionML115 ≥98%
- Packaging5mg
- Price$356
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0034434
- Product descriptionML115 99.98%
- Packaging25mg
- Price$867
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E5P8 | ML-115 99% | 5mg | $89 | 2026-05-30 | Buy |
| aablocks | AA01E5P8 | ML-115 99% | 10mg | $133 | 2026-05-30 | Buy |
| aablocks | AA01E5P8 | ML-115 99% | 25mg | $253 | 2026-05-30 | Buy |
| aablocks | AA01E5P8 | ML-115 99 | 200mg | $1364 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y227984 | ML115 97.00% | 25MG | $795 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227984 | ML115 97.00% | 100MG | $1500 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227984 | ML115 97.00% | 5MG | $285 | 2026-05-27 | Buy |
| AK Scientific | SYN5305 | ML115 | 10mg | $362 | 2021-12-16 | Buy |
| AK Scientific | SYN5305 | ML115 | 100mg | $2237 | 2021-12-16 | Buy |
| Cayman Chemical | 15178 | ML-115 ≥98% | 5mg | $392 | 2026-04-30 | Buy |
| Cayman Chemical | 15178 | ML115 ≥98% | 1mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 15178 | ML-115 ≥98% | 1mg | $102 | 2026-04-30 | Buy |
| Cayman Chemical | 15178 | ML115 ≥98% | 500μg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 15178 | ML-115 ≥98% | 500μg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 15178 | ML115 ≥98% | 5mg | $356 | 2024-03-01 | Buy |
| ChemScene | CS-0034434 | ML115 99.98% | 25mg | $867 | 2026-06-04 | Buy |
Properties
Boiling point :422.9±45.0 °C(Predicted)
Density :1.389±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMSO: 16 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :9.26±0.70(Predicted)
color :White to off-white
InChI :InChI=1S/C15H15ClN2O4/c1-20-13-6-10(14(21-2)5-9(13)16)17-15(19)11-7-12(22-18-11)8-3-4-8/h5-8H,3-4H2,1-2H3,(H,17,19)
InChIKey :FMWABCRYNLCXOJ-UHFFFAOYSA-N
SMILES :O1C(C2CC2)=CC(C(NC2=CC(OC)=C(Cl)C=C2OC)=O)=N1
Density :1.389±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMSO: 16 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :9.26±0.70(Predicted)
color :White to off-white
InChI :InChI=1S/C15H15ClN2O4/c1-20-13-6-10(14(21-2)5-9(13)16)17-15(19)11-7-12(22-18-11)8-3-4-8/h5-8H,3-4H2,1-2H3,(H,17,19)
InChIKey :FMWABCRYNLCXOJ-UHFFFAOYSA-N
SMILES :O1C(C2CC2)=CC(C(NC2=CC(OC)=C(Cl)C=C2OC)=O)=N1
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | |||||||
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Description
Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer. ML115 is an isoxazole carboxamide that acts as a cell-permeable STAT3 activator (EC50 = 2 nM) and is more than 28,000-fold selective for STAT3 over STAT1 and NF-κB. It shows no cytotoxicity against HT-1080 or NIH-3T3 cells. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene, and enhances STAT3 activation by the pro-inflammatory cytokine IL-6. As the maintenance of pluripotency in mouse embryonic stem cells requires continued activation of STAT3, ML115 may be useful in maintaining embryonic stem cells in an undifferentiated state.More related product prices
Nodinitib-1 1382481-79-9 ML-098 ML-228 1-(4-(4-(benzo[d][1,3]dioxole-5-carbonyl)piperazin-1-yl)phenyl)ethan-1-one ML355 ML349 1062368-49-3 ML291Related product price
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Suppliers and manufacturers
TargetMol Chemicals Inc.
Suzhou Zhuyanke Biopharmaceutical Co., Ltd.
Suzhou Zhixin Biotechnology Co., Ltd.
BOC Sciences
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
TargetMol Chemicals Inc.
