Oclacitinib
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- $9 - $2395.3
- Product name: Oclacitinib
- CAS: 1208319-26-9
- MF: C15H23N5O2S
- MW: 337.44
- EINECS:950-980-7
- MDL Number:MFCD25976611
- Synonyms:Oclacitinib PF-03394197;trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-cyclohexanemethanesulfonamide;CyclohexaneMethanesulfonaMide, N-Methyl-4-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-, trans-;N-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide;N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide;Oclacitinib;PF 03394197;Oclacitinib?, >98%
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 0.05g
- 50mg
- 0.1g
- 100mg
- 100.00mg
- 0.25g
- 250.00mg
- 250mg
- 0.5g
- 1g
- 1.00g
- 5g
- Manufactureraablocks
- Product numberAA008TFW
- Product descriptionN-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98%
- Packaging100mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TFW
- Product descriptionN-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98%
- Packaging250mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TFW
- Product descriptionN-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98%
- Packaging10mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TFW
- Product descriptionN-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98%
- Packaging5mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TFW
- Product descriptionN-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98%
- Packaging2mg
- Price$9
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33885
- Product descriptionPF03394197 98%
- Packaging100MG
- Price$28
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33885
- Product descriptionPF03394197 98%
- Packaging100MG
- Price$28
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4057DF
- Product descriptionOclacitinib
- Packaging50mg
- Price$785
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5752
- Product descriptionOclacitinib
- Packaging50mg
- Price$968
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002505
- Product descriptionOCLACITINIB 95.00%
- Packaging5MG
- Price$499.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5960
- Product descriptionPF-03394197(Oclacitinib)
- Packaging50mg
- Price$231
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5960
- Product descriptionPF-03394197(Oclacitinib)
- Packaging10mg
- Price$77
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5960
- Product descriptionPF-03394197(Oclacitinib)
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5960
- Product descriptionPF-03394197(Oclacitinib)
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146233
- Product descriptionPF-03394197(Oclacitinib) >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146233
- Product descriptionPF-03394197(Oclacitinib) >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TFW | N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98% | 100mg | $52 | 2026-05-28 | Buy |
| aablocks | AA008TFW | N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98% | 250mg | $68 | 2026-05-28 | Buy |
| aablocks | AA008TFW | N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98% | 10mg | $19 | 2026-05-28 | Buy |
| aablocks | AA008TFW | N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98% | 5mg | $12 | 2026-05-28 | Buy |
| aablocks | AA008TFW | N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide 98% | 2mg | $9 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33885 | PF03394197 98% | 100MG | $28 | 2026-05-25 | Buy |
| ACHEMBLOCK | O33885 | PF03394197 98% | 100MG | $28 | 2026-05-27 | Buy |
| AK Scientific | 4057DF | Oclacitinib | 50mg | $785 | 2021-12-16 | Buy |
| AK Scientific | SYN5752 | Oclacitinib | 50mg | $968 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002505 | OCLACITINIB 95.00% | 5MG | $499.1 | 2021-12-16 | Buy |
| ApexBio Technology | B5960 | PF-03394197(Oclacitinib) | 50mg | $231 | 2026-05-06 | Buy |
| ApexBio Technology | B5960 | PF-03394197(Oclacitinib) | 10mg | $77 | 2026-05-06 | Buy |
| ApexBio Technology | B5960 | PF-03394197(Oclacitinib) | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | B5960 | PF-03394197(Oclacitinib) | 5mg | $140 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146233 | PF-03394197(Oclacitinib) >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146233 | PF-03394197(Oclacitinib) >98% | 100mg | $765 | 2021-12-16 | Buy |
Properties
Melting point :226-228°C
Density :1.316±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20-25℃
storage temp. :Refrigerator, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :11.59±0.40(Predicted)
form :Solid
color :Off-White to Pale Beige
InChI :InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-
InChIKey :HJWLJNBZVZDLAQ-HAQNSBGRSA-N
SMILES :[C@@H]1(CS(NC)(=O)=O)CC[C@@H](N(C)C2N=CN=C3NC=CC3=2)CC1
LogP :1.38 at 35℃ and pH7
Density :1.316±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20-25℃
storage temp. :Refrigerator, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :11.59±0.40(Predicted)
form :Solid
color :Off-White to Pale Beige
InChI :InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-
InChIKey :HJWLJNBZVZDLAQ-HAQNSBGRSA-N
SMILES :[C@@H]1(CS(NC)(=O)=O)CC[C@@H](N(C)C2N=CN=C3NC=CC3=2)CC1
LogP :1.38 at 35℃ and pH7
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Oclacitinib is an orally bioavailable, broad spectrum JAK inhibitor (IC50s = 10, 18, 99, and 84 nM for JAK1, JAK2, JAK3, and JAK4, respectively). It is specific for JAK isozymes against a large panel of other kinases. Oclacitinib blocks cell-based JAK signaling induced by IL-2, IL-4, IL-6, IL-13, or IL-31 with IC50 values ranging from 36 to 249 nM. Oral oclacitinib is used against atopic dermatitis with pruritus in dogs.More related product prices
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