PHA-793887
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- $16 - $9556.47
- Product name: PHA-793887
- CAS: 718630-59-2
- MF: C19H31N5O2
- MW: 361.48
- EINECS:
- MDL Number:MFCD17169992
- Synonyms:3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;PHA-793887;N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide PHA-793887;PHA-793887 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;PHA-793887;PHA793887;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c];PHA-793887 USP/EP/BP
92 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO
- 2mg
- 5mg
- 10mg
- 25.00mg
- 25mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250mg
- 25 mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1G
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging1mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging2mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging5mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging10mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging25mg
- Price$64
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging50mg
- Price$102
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging100mg
- Price$163
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005F9R
- Product descriptionButanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98%
- Packaging250mg
- Price$268
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging25MG
- Price$245
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging25MG
- Price$245
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging100MG
- Price$585
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging100MG
- Price$585
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging5MG
- Price$100
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging5MG
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging1G
- Price$1650
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101229
- Product description3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98%
- Packaging1G
- Price$1650
- Updated2026-05-27
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 1mg | $16 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 2mg | $20 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 5mg | $28 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 10mg | $38 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 25mg | $64 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 50mg | $102 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 100mg | $163 | 2026-05-28 | Buy |
| aablocks | AA005F9R | Butanamide, 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]- 98% | 250mg | $268 | 2026-05-28 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 25MG | $245 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 25MG | $245 | 2026-05-27 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 100MG | $585 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 100MG | $585 | 2026-05-27 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 5MG | $100 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 5MG | $100 | 2026-05-27 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 1G | $1650 | 2026-05-25 | Buy |
| ACHEMBLOCK | T101229 | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide 98% | 1G | $1650 | 2026-05-27 | Buy |
Properties
Melting point :>147°C (dec.)
Boiling point :596.2±50.0 °C(Predicted)
Density :1.176±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol(Slightly)
pka :13.74±0.40(Predicted)
form :Solid
color :Off-White to Pale Yellow
Stability :Hygroscopic
InChI :InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)
InChIKey :HUXYBQXJVXOMKX-UHFFFAOYSA-N
SMILES :C(NC1=NNC2C(C)(C)N(C(C3CCN(C)CC3)=O)CC=21)(=O)CC(C)C
Boiling point :596.2±50.0 °C(Predicted)
Density :1.176±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol(Slightly)
pka :13.74±0.40(Predicted)
form :Solid
color :Off-White to Pale Yellow
Stability :Hygroscopic
InChI :InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)
InChIKey :HUXYBQXJVXOMKX-UHFFFAOYSA-N
SMILES :C(NC1=NNC2C(C)(C)N(C(C3CCN(C)CC3)=O)CC=21)(=O)CC(C)C
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | |||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
PHA-793887 is a pyrrolo[3,4-c]pyrazole that inhibits cyclin-dependent kinases Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk7/cyclin H with IC50 values of 8, 8, 5, and 10 nM, respectively. It is more than 6-fold selective for these kinases over Cdk1/cyclin B, Cdk4/cyclin D1, Cdk9/cyclin T, and GSK3β (IC50s = 60, 62, 138, and 79 nM, respectively). PHA-793887 is cytotoxic to human ovarian A2780, colon HCT-116, pancreatic BX-PC3, and leukemic K562, KU812, KCL22, and TOM1 cells both in vitro and in xenograft models. This compound has been examined in patients with solid tumors in phase 1 clinical trials.More related product prices
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Suppliers and manufacturers
CONIER CHEM AND PHARMA LIMITED
Antai Fine Chemical Technology Co.,Limited
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hunan Jibang Biological Technology Co., LTD
HANGZHOU LEAP CHEM CO., LTD.
Coresyn Pharmatech Co., Ltd.
![3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide](https://img.chemicalbook.com/ProductImageEN/2020-1/small/41c31098-330f-4f89-a4c8-db449616603e.jpg){kind=small}
