SIRTINOL
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- $18 - $1675
- Product name: SIRTINOL
- CAS: 410536-97-9
- MF: C26H22N2O2
- MW: 394.47
- EINECS:
- MDL Number:MFCD00810186
- Synonyms:2-[(2-HYDROXYNAPHTHALEN-1-YLMETHYLENE)AMINO]-N-(1-PHENETHYL)BENZAMIDE;SIRTINOL;SIR TWO INHIBITOR NAPHTHOL;(E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide;2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide;2-{[(2-hydroxynaphthalen-1-yl)Methylidene]aMino}-N-(2-phenylethyl)benzaMide;{2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]}-N-(1-phenethyl)benzamide (Sirtinol);Sirtinol - CAS 410536-97-9 - Calbiochem
106 prices
Selected condition：
Brand
- aablocks
- Abosyn
- ACHEMBLOCK
- Adipogen Life Sciences
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Aronis compounds
- AvaChem
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynChem
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- 1mg
- 50
- 5mg
- 10mg
- 10
- 0.025g
- 25mg
- 50MG
- 100MG
- 250mg
- 0.25g
- 1g
- 5g
- 10g
- Manufactureraablocks
- Product numberAA00BYAU
- Product descriptionSirtinol 98%
- Packaging1mg
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYAU
- Product descriptionSirtinol 98%
- Packaging5mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYAU
- Product descriptionSirtinol 98%
- Packaging10mg
- Price$65
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYAU
- Product descriptionSirtinol 97%
- Packaging250mg
- Price$185
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYAU
- Product descriptionSirtinol 97%
- Packaging1g
- Price$452
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BYAU
- Product descriptionSirtinol 97%
- Packaging5g
- Price$1675
- Updated2026-05-28
- Buy
- ManufacturerAbosyn
- Product number61-0141
- Product description(E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide 95-98%
- Packaging0.25g
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228858
- Product descriptionSirtinol 97.00%
- Packaging50MG
- Price$430
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228858
- Product descriptionSirtinol 97.00%
- Packaging100MG
- Price$640
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M025
- Product descriptionSirtinol ≥98%(NMR)
- Packaging25mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M025
- Product descriptionSirtinol ≥98%(NMR)
- Packaging25mg
- Price$165
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M005
- Product descriptionSirtinol ≥98%(NMR)
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M001
- Product descriptionSirtinol ≥98%(NMR)
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0055-M001
- Product descriptionSirtinol ≥98%(NMR)
- Packaging1mg
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerAHH
- Product numberMT-15353
- Product description2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide 95%
- Packaging0.025g
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-15353
- Product description2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl) benzamide 97%
- Packaging0.025g
- Price$418
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BYAU | Sirtinol 98% | 1mg | $21 | 2026-05-28 | Buy |
| aablocks | AA00BYAU | Sirtinol 98% | 5mg | $42 | 2026-05-28 | Buy |
| aablocks | AA00BYAU | Sirtinol 98% | 10mg | $65 | 2026-05-28 | Buy |
| aablocks | AA00BYAU | Sirtinol 97% | 250mg | $185 | 2026-05-28 | Buy |
| aablocks | AA00BYAU | Sirtinol 97% | 1g | $452 | 2026-05-28 | Buy |
| aablocks | AA00BYAU | Sirtinol 97% | 5g | $1675 | 2026-05-28 | Buy |
| Abosyn | 61-0141 | (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide 95-98% | 0.25g | $225 | 2021-12-16 | Buy |
| ACHEMBLOCK | Y228858 | Sirtinol 97.00% | 50MG | $430 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228858 | Sirtinol 97.00% | 100MG | $640 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M025 | Sirtinol ≥98%(NMR) | 25mg | $165 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M025 | Sirtinol ≥98%(NMR) | 25mg | $165 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M005 | Sirtinol ≥98%(NMR) | 5mg | $55 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M001 | Sirtinol ≥98%(NMR) | 1mg | $30 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-0055-M001 | Sirtinol ≥98%(NMR) | 1mg | $30 | 2026-05-06 | Buy |
| AHH | MT-15353 | 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide 95% | 0.025g | $418 | 2021-12-16 | Buy |
| AHH | MT-15353 | 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl) benzamide 97% | 0.025g | $418 | 2026-05-25 | Buy |
Properties
Melting point :119-120℃
Boiling point :659.2±50.0 °C(Predicted)
Density :1.16
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :Yellow solid
pka :7.85±0.50(Predicted)
color :Pale yellow
Water Solubility :Soluble in water, DMSO and methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,29H,1H3,(H,28,30)
InChIKey :UXJFDYIHRJGPFS-UHFFFAOYSA-N
SMILES :C(NC(C1=CC=CC=C1)C)(=O)C1=CC=CC=C1N=CC1=C2C(C=CC=C2)=CC=C1O
Boiling point :659.2±50.0 °C(Predicted)
Density :1.16
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :Yellow solid
pka :7.85±0.50(Predicted)
color :Pale yellow
Water Solubility :Soluble in water, DMSO and methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,29H,1H3,(H,28,30)
InChIKey :UXJFDYIHRJGPFS-UHFFFAOYSA-N
SMILES :C(NC(C1=CC=CC=C1)C)(=O)C1=CC=CC=C1N=CC1=C2C(C=CC=C2)=CC=C1O
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 μM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 μM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells. In plants, sirtinol can be metabolized to 2-hydroxy-1-naphthoic acid, which activates auxin signaling and alters plant growth and development.Related product price
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