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ChemicalBook >> CAS DataBase List >> Silybin

Silybin

Silybin price.
  • $5 - $1631
  • Product name: Silybin
  • CAS: 22888-70-6
  • MF: C25H22O10
  • MW: 482.44
  • EINECS:245-302-5
  • MDL Number:MFCD00872186
  • Synonyms:Silybin-A ,98%;Silybin (50 mg);Silybin, 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin;Silybin，Silymarin;(2R)-2α-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3β,5,7-trihydroxy-4H-1-benzopyran-4-one;(2R,3R)-2-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Flavobion;silliver
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  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00I4FF
  • Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I4FF
  • Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
  • Packaging1g
  • Price$18
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I4FF
  • Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
  • Packaging5g
  • Price$46
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I4FF
  • Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
  • Packaging10g
  • Price$87
  • Updated2026-05-29
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-S0276-G010
  • Product descriptionSilibinin ≥98%(HPLC)
  • Packaging10g
  • Price$73
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-S0276-G010
  • Product descriptionSilibinin ≥98%(HPLC)
  • Packaging10g
  • Price$65
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-S0276-G100
  • Product descriptionSilibinin ≥98%(HPLC)
  • Packaging100g
  • Price$579
  • Updated2026-05-06
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  • ManufacturerAHH
  • Product numberAPI-1488
  • Product descriptionSilybin 98%
  • Packaging500g
  • Price$700
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1488
  • Product descriptionSilybin 97%
  • Packaging500g
  • Price$700
  • Updated2026-05-26
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  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging25g
  • Price$275
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging5g
  • Price$66
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging10g
  • Price$76
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging1g
  • Price$12
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging100mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026191
  • Product descriptionSILYBIN 95.00%
  • Packaging1G
  • Price$614.87
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I4FF (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98% 1mg $8 2026-05-29 Buy
aablocks AA00I4FF (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98% 1g $18 2026-05-29 Buy
aablocks AA00I4FF (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98% 5g $46 2026-05-29 Buy
aablocks AA00I4FF (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98% 10g $87 2026-05-29 Buy
Adipogen Life Sciences CDX-S0276-G010 Silibinin ≥98%(HPLC) 10g $73 2026-05-06 Buy
Adipogen Life Sciences CDX-S0276-G010 Silibinin ≥98%(HPLC) 10g $65 2021-12-16 Buy
Adipogen Life Sciences CDX-S0276-G100 Silibinin ≥98%(HPLC) 100g $579 2026-05-06 Buy
AHH API-1488 Silybin 98% 500g $700 2021-12-16 Buy
AHH API-1488 Silybin 97% 500g $700 2026-05-26 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 25g $275 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 5g $66 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 10g $76 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 1g $12 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 25mg $5 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 100mg $6 2021-12-16 Buy
American Custom Chemicals Corporation API0026191 SILYBIN 95.00% 1G $614.87 2021-12-16 Buy

Properties

Melting point :164-174°C
Boiling point :793.0±60.0 °C(Predicted)
alpha :D20 +11° (c = 0.25 in acetone + alcohol)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Acetone (Sparingly), DMSO, Methano (Sparingly)
form :Solid
pka :pKa 6.42±0.04 (Uncertain)
color :Pale Yellow
Water Solubility :54mg/L(24.99 ºC)
Merck :13,8607
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChIKey :SEBFKMXJBCUCAI-HKTJVKLFSA-N
SMILES :C([C@H]1OC2=CC=C([C@@H]3[C@H](C(C4=C(C=C(C=C4O3)O)O)=O)O)C=C2O[C@@H]1C1C=CC(=C(C=1)OC)O)O
LogP :4.232 (est)
CAS DataBase Reference :22888-70-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.

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