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ChemicalBook >> CAS DataBase List >> TMP269

TMP269

$37 - $2121
Product name: TMP269
CAS: 1314890-29-3
MF: C25H21F3N4O3S
MW: 514.52
EINECS:
MDL Number:MFCD26522023
Synonyms:N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide TMP269;TMP269 N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide;BenzaMide, N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]Methyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]-;TMP269;N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)Methyl)-3-(5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl)benzaMide;N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide;TMP269, >=98%;N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxad

Price62 Properties Safety Information Description

62 prices

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Brand

aablocks
Absolute Chiral
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
TRC

Package

10mM*1mLinDMSO(Solution)
1mg
5mg
10mg
25mg
50mg
10mM*1mLinDMSO(Solid+Solvent)
100mg
200mg
10mM*1mLinDMSO
250mg
1G
10mM(in 1mL DMSO)
500mg
10mM(in1mLDMSO)

Manufactureraablocks
Product numberAA009CCC
Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥95%
Packaging1mg
Price$41
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CCC
Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98%
Packaging5mg
Price$55
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CCC
Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98%
Packaging10mg
Price$99
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CCC
Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+%
Packaging50mg
Price$131
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CCC
Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+%
Packaging100mg
Price$157
Updated2026-05-28
Buy

ManufacturerAbsolute Chiral
Product numberO1152-00-N
Product descriptionN-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95%
Packaging25mg
Price$150
Updated2026-05-23
Buy

ManufacturerAbsolute Chiral
Product numberO1152-00-N
Product descriptionN-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95%
Packaging25mg
Price$150
Updated2021-12-16
Buy

ManufacturerACHEMBLOCK
Product numberO33755
Product descriptionTMP269 98%
Packaging25MG
Price$155
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberO33755
Product descriptionTMP269 98%
Packaging25MG
Price$155
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberO33755
Product descriptionTMP269 98%
Packaging100MG
Price$500
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberO33755
Product descriptionTMP269 98%
Packaging100MG
Price$500
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberO33755
Product descriptionTMP269 98%
Packaging1G
Price$1580
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberO33755
Product descriptionTMP269 98%
Packaging1G
Price$1580
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2760AH
Product descriptionN-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
Packaging250mg
Price$925
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2760AH
Product descriptionN-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
Packaging1g
Price$2121
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8806
Product descriptionTMP269
Packaging10mg
Price$180
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA009CCC	N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥95%	1mg	$41	2026-05-28	Buy
aablocks	AA009CCC	N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98%	5mg	$55	2026-05-28	Buy
aablocks	AA009CCC	N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98%	10mg	$99	2026-05-28	Buy
aablocks	AA009CCC	N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+%	50mg	$131	2026-05-28	Buy
aablocks	AA009CCC	N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+%	100mg	$157	2026-05-28	Buy
Absolute Chiral	O1152-00-N	N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95%	25mg	$150	2026-05-23	Buy
Absolute Chiral	O1152-00-N	N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95%	25mg	$150	2021-12-16	Buy
ACHEMBLOCK	O33755	TMP269 98%	25MG	$155	2026-05-25	Buy
ACHEMBLOCK	O33755	TMP269 98%	25MG	$155	2026-05-27	Buy
ACHEMBLOCK	O33755	TMP269 98%	100MG	$500	2026-05-25	Buy
ACHEMBLOCK	O33755	TMP269 98%	100MG	$500	2026-05-27	Buy
ACHEMBLOCK	O33755	TMP269 98%	1G	$1580	2026-05-25	Buy
ACHEMBLOCK	O33755	TMP269 98%	1G	$1580	2026-05-27	Buy
AK Scientific	2760AH	N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide	250mg	$925	2021-12-16	Buy
AK Scientific	2760AH	N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide	1g	$2121	2021-12-16	Buy
ApexBio Technology	A8806	TMP269	10mg	$180	2021-12-16	Buy

Next Last

Properties

Density :1.347±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :≥23 mg/mL in DMSO; insoluble in H2O; ≥21 mg/mL in EtOH with ultrasonic
form :solid
pka :13.66±0.46(Predicted)
color :White to off-white
SMILES :FC(F)(C1=NC(C2=CC(C(NCC3(C4=NC(C5=CC=CC=C5)=CS4)CCOCC3)=O)=CC=C2)=NO1)F

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321	Specific treatment (see … on this label).
P330	Rinse mouth.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P501	Dispose of contents/container to..…

Description

While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which include HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. TMP269 is a cell-permeable inhibitor of class IIa HDACs (IC50s = 126, 80, 36, and 19 nM for HDAC4, 5, 7, and 9, respectively). It contains a metal-binding group, trifluoromethyloxadiazole that confers selectivity for class IIa HDACs.

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Suppliers and manufacturers

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$1.00
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TMP269

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Description

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