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ChemicalBook >> CAS DataBase List >> TYRPHOSTIN A25

TYRPHOSTIN A25

TYRPHOSTIN A25 price.
  • $28 - $2000
  • Product name: TYRPHOSTIN A25
  • CAS: 118409-58-8
  • MF: C10H6N2O3
  • MW: 202.17
  • EINECS:
  • MDL Number:MFCD00133900
  • Synonyms:[3,4,5-TRIHYDROXYBENZYLIDENE]MALONONITRILE;AG 82;ALPHA-CYANO-(3,4,5-TRIHYDROXY)CINNAMONITRILE;RG-50875;RARECHEM AL BX 0070;TYRPHOSTIN RG 50875;TYRPHOSTIN AG 82;TYRPHOSTIN A25
36 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 125mg
  • 250MG
  • Manufactureraablocks
  • Product numberAA001NIW
  • Product description2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95%
  • Packaging5mg
  • Price$31
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001NIW
  • Product description2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95%
  • Packaging10mg
  • Price$55
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001NIW
  • Product description2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95%
  • Packaging25mg
  • Price$129
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001NIW
  • Product description2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95%
  • Packaging50mg
  • Price$228
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227153
  • Product descriptionAG-82 97.00%
  • Packaging250MG
  • Price$640
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227153
  • Product descriptionAG-82 97.00%
  • Packaging100MG
  • Price$320
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2089AH
  • Product descriptionTyrphostinA25
  • Packaging5mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001451
  • Product descriptionTYRPHOSTIN A-25 95.00%
  • Packaging5MG
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001451
  • Product descriptionTYRPHOSTIN A-25 95.00%
  • Packaging25MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001451
  • Product descriptionTYRPHOSTIN A-25 95.00%
  • Packaging250MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4760
  • Product descriptionAG-82
  • Packaging25mg
  • Price$175
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4760
  • Product descriptionAG-82
  • Packaging50mg
  • Price$311
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4760
  • Product descriptionAG 82
  • Packaging25mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4760
  • Product descriptionAG 82
  • Packaging50mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1705009
  • Product descriptionTyrphostin A25 98.98%
  • Packaging50mg
  • Price$230
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1705009
  • Product descriptionTyrphostin A25 98.98%
  • Packaging10mg
  • Price$120
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001NIW 2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95% 5mg $31 2026-05-28 Buy
aablocks AA001NIW 2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95% 10mg $55 2026-05-28 Buy
aablocks AA001NIW 2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95% 25mg $129 2026-05-28 Buy
aablocks AA001NIW 2-[(3,4,5-Trihydroxyphenyl)methylidene]propanedinitrile ≥95% 50mg $228 2026-05-28 Buy
ACHEMBLOCK Y227153 AG-82 97.00% 250MG $640 2026-05-27 Buy
ACHEMBLOCK Y227153 AG-82 97.00% 100MG $320 2026-05-27 Buy
AK Scientific 2089AH TyrphostinA25 5mg $128 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001451 TYRPHOSTIN A-25 95.00% 5MG $137.5 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001451 TYRPHOSTIN A-25 95.00% 25MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001451 TYRPHOSTIN A-25 95.00% 250MG $1732.5 2021-12-16 Buy
ApexBio Technology C4760 AG-82 25mg $175 2026-05-06 Buy
ApexBio Technology C4760 AG-82 50mg $311 2026-05-06 Buy
ApexBio Technology C4760 AG 82 25mg $131 2021-12-16 Buy
ApexBio Technology C4760 AG 82 50mg $233 2021-12-16 Buy
Biorbyt Ltd orb1705009 Tyrphostin A25 98.98% 50mg $230 2026-05-06 Buy
Biorbyt Ltd orb1705009 Tyrphostin A25 98.98% 10mg $120 2026-05-06 Buy

Properties

Melting point :~220°C dec.
Boiling point :500.8±50.0 °C(Predicted)
Density :1.569±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >50 mg/mL, clear, yellow to orange
form :Dark yellow solid
pka :7.10±0.23(Predicted)
color :Yellow Green
Stability :Light Sensitive
CAS DataBase Reference :118409-58-8

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Tyrphostin A25 is a cell-permeable, competitive and reversible inhibitor of substrate binding on protein tyrosine kinases. In cultured rat hepatocytes, Tyrphostin A25 has been shown to inhibit endocytosis of tyramine-cellobiose-asialoorosomucoid (TC-AOM). It has also shown to inhibit neuromedin B-induced phosphorylation of focal adhesion kinase (p125FAK). Inhibits EGFR (epidermal growth factor receptor) tyrosine kinase (IC50=3 M ) and the GTPase activity of transducin. In small cell lung cancer cells tyrphostin A25 has been observed to obstruct neuropeptide and basal stimulated growth. In addition it has blocked the induction of inducible NO synthase in glial cells and in human leukemic cell lines has induced apoptosis.

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