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ChemicalBook >> CAS DataBase List >> ml390

ml390

ml390 price.
  • $17 - $2707
  • Product name: ml390
  • CAS: 2029049-79-2
  • MF: C21H21F3N2O3
  • MW: 406.4
  • EINECS:-0
  • MDL Number:
  • Synonyms:ml390;Benzamide, N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethoxy)-;ER-HoxA9,Dihydroorotate Dehydrogenase,inhibit,AML,ML 390,differentiatio,U937,DHODH,ML390,myeloid,ML-390,Inhibitor,THP1;(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide;ML390, 10 mM in DMSO
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  • aablocks
  • ACHEMBLOCK
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
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  • 5mg
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  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 25mg
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  • 100mg
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  • 1g
  • Manufactureraablocks
  • Product numberAA01EPOJ
  • Product description(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99
  • Packaging25mg
  • Price$79
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01EPOJ
  • Product description(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99
  • Packaging50mg
  • Price$111
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01EPOJ
  • Product description(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99
  • Packaging100mg
  • Price$182
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01EPOJ
  • Product description(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99%
  • Packaging10mg
  • Price$45
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01EPOJ
  • Product description(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99%
  • Packaging5mg
  • Price$27
  • Updated2026-05-30
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  • Manufactureraablocks
  • Product numberAA01EPOJ
  • Product description(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99%
  • Packaging1mg
  • Price$17
  • Updated2026-05-30
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  • ManufacturerACHEMBLOCK
  • Product numberZ238249
  • Product descriptionML390 98%
  • Packaging100MG
  • Price$240
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238249
  • Product descriptionML390 98%
  • Packaging25MG
  • Price$110
  • Updated2026-05-27
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  • ManufacturerApexBio Technology
  • Product numberB7824
  • Product descriptionML390
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB7824
  • Product descriptionML390
  • Packaging1mg
  • Price$50
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB7824
  • Product descriptionML390
  • Packaging5mg
  • Price$53
  • Updated2026-05-06
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  • ManufacturerArctom
  • Product numberHY-100688
  • Product descriptionML390 99.72%
  • Packaging10mg
  • Price$81
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-100688
  • Product descriptionML390 99.72%
  • Packaging25mg
  • Price$181
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-100688
  • Product descriptionML390 99.72%
  • Packaging50mg
  • Price$266
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-100688
  • Product descriptionML390 99.72%
  • Packaging100mg
  • Price$428
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100688
  • Product descriptionML390 99.72%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$53
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EPOJ (R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99 25mg $79 2026-05-30 Buy
aablocks AA01EPOJ (R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99 50mg $111 2026-05-30 Buy
aablocks AA01EPOJ (R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99 100mg $182 2026-05-30 Buy
aablocks AA01EPOJ (R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99% 10mg $45 2026-05-30 Buy
aablocks AA01EPOJ (R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99% 5mg $27 2026-05-30 Buy
aablocks AA01EPOJ (R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide 99% 1mg $17 2026-05-30 Buy
ACHEMBLOCK Z238249 ML390 98% 100MG $240 2026-05-27 Buy
ACHEMBLOCK Z238249 ML390 98% 25MG $110 2026-05-27 Buy
ApexBio Technology B7824 ML390 5mg $190 2021-12-16 Buy
ApexBio Technology B7824 ML390 1mg $50 2026-05-06 Buy
ApexBio Technology B7824 ML390 5mg $53 2026-05-06 Buy
Arctom HY-100688 ML390 99.72% 10mg $81 2026-05-26 Buy
Arctom HY-100688 ML390 99.72% 25mg $181 2026-05-26 Buy
Arctom HY-100688 ML390 99.72% 50mg $266 2026-05-26 Buy
Arctom HY-100688 ML390 99.72% 100mg $428 2026-05-26 Buy
Arctom HY-100688 ML390 99.72% 10mM*1mLinDMSO(Solution) $53 2026-05-26 Buy

Properties

Boiling point :599.7±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥40.6 mg/mL in DMSO; insoluble in H2O; ≥17.47 mg/mL in EtOH
form :solid
pka :13.65±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML-390 is an inhibitor of dihydroorotate dehydrogenase (DHODH), the enzyme that converts dihydroorotate to orotate during de novo pyrimidine synthesis. In acute myeloid leukemia, leukemic myeloblast development is halted at an immature stage leading to perpetual self-renewal rather than differentiation. ML-390 induces differentiation in the acute myeloid leukemia cell lines U937 (murine) and THP-1 (human) cell lines with an EC50 value of approximately 2 μM.

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