pilaralisib
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- $12 - $1500
- Product name: pilaralisib
- CAS: 934526-89-3
- MF: C25H25ClN6O4S
- MW: 541.02
- EINECS:
- MDL Number:MFCD26142605
- Synonyms:PILARALISIB (XL147);SAR245408;XL 147;XL-147,Pilaralisib, SAR245408;XL147(pilaralisib);2-amino-N-[3-[[3-(2-chloro-5-methoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide;2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide;Pilaralisib (XL-147);pilaralisib;Propanamide, 2-amino-N-[3-[[[3-[(2-chloro-5-methoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-2-methyl-
51 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 2mg
- 5mg
- 10mg
- 10mM*1mLinDMSO
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00GU4N
- Product description2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU4N
- Product description2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99%
- Packaging5mg
- Price$26
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU4N
- Product description2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99%
- Packaging10mg
- Price$40
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU4N
- Product description2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99%
- Packaging25mg
- Price$78
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU4N
- Product description2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99%
- Packaging50mg
- Price$95
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GU4N
- Product description2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99%
- Packaging100mg
- Price$114
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22492
- Product descriptionpilaralisib 98%
- Packaging100MG
- Price$85
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22492
- Product descriptionpilaralisib 98%
- Packaging25MG
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22492
- Product descriptionpilaralisib 98%
- Packaging1G
- Price$375
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9609BB
- Product descriptionPilaralisib
- Packaging1g
- Price$1060
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-16526
- Product descriptionPilaralisib 98.81%
- Packaging100mg
- Price$456
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16526
- Product descriptionPilaralisib 98.81%
- Packaging10mg
- Price$114
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16526
- Product descriptionPilaralisib 98.81%
- Packaging50mg
- Price$285
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16526
- Product descriptionPilaralisib 98.81%
- Packaging5mg
- Price$72
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16526
- Product descriptionPilaralisib 98.81%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$81
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-16526
- Product descriptionPilaralisib 98.81%
- Packaging10mM*1mLinDMSO(Solution)
- Price$85
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GU4N | 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00GU4N | 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99% | 5mg | $26 | 2026-05-28 | Buy |
| aablocks | AA00GU4N | 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99% | 10mg | $40 | 2026-05-28 | Buy |
| aablocks | AA00GU4N | 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99% | 25mg | $78 | 2026-05-28 | Buy |
| aablocks | AA00GU4N | 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99% | 50mg | $95 | 2026-05-28 | Buy |
| aablocks | AA00GU4N | 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide 99% | 100mg | $114 | 2026-05-28 | Buy |
| ACHEMBLOCK | L22492 | pilaralisib 98% | 100MG | $85 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22492 | pilaralisib 98% | 25MG | $35 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22492 | pilaralisib 98% | 1G | $375 | 2026-05-27 | Buy |
| AK Scientific | 9609BB | Pilaralisib | 1g | $1060 | 2021-12-16 | Buy |
| Arctom | HY-16526 | Pilaralisib 98.81% | 100mg | $456 | 2026-05-26 | Buy |
| Arctom | HY-16526 | Pilaralisib 98.81% | 10mg | $114 | 2026-05-26 | Buy |
| Arctom | HY-16526 | Pilaralisib 98.81% | 50mg | $285 | 2026-05-26 | Buy |
| Arctom | HY-16526 | Pilaralisib 98.81% | 5mg | $72 | 2026-05-26 | Buy |
| Arctom | HY-16526 | Pilaralisib 98.81% | 10mM*1mLinDMSO(Solid+Solvent) | $81 | 2026-05-26 | Buy |
| Arctom | HY-16526 | Pilaralisib 98.81% | 10mM*1mLinDMSO(Solution) | $85 | 2026-05-26 | Buy |
Properties
Melting point :216-220oC
Density :1.458±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly)
pka :6.33±0.30(Predicted)
form :Solid
color :Light Yellow to Yellow
Density :1.458±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly)
pka :6.33±0.30(Predicted)
form :Solid
color :Light Yellow to Yellow
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. Pilaralisib is a methylbenzenesulfonamide derivative that reversibly inhibits class I PI3Ks (IC50s = 39, 36, 23, and 383 nM for p110α, -δ, -γ, and -β, respectively). It has been shown to abrogate Akt and S6 kinase phosphorylation, reduce cyclin D1 and retinoblastoma protein, and upregulate the CDK inhibitor p27, inhibiting cell proliferation. In HER2-overexpressing breast cancer cells, cotreatment with the HER2 inhibitors trastuzumab or lapatinib are reported to sensitize tumor cells to the growth inhibitory effect of pilaralisib. This compound has been evaluated in clinical trials in patients with advanced solid tumors.Related product price
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XL147
$32-2464 -
XL019
$18-3980 -
BMS 833923
$26-1802
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
PT CHEM GROUP LIMITED
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
