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ChemicalBook >> CAS DataBase List >> BMS 833923

BMS 833923

$26 - $1802
Product name: BMS 833923
CAS: 1059734-66-5
MF: C30H27N5O
MW: 473.57
EINECS:
MDL Number:MFCD25976660
Synonyms:BMS 833923;XL 139;XL139;XL-139;BMS-833923 (XL-139);N-[2-Methyl-5-[(methylamino)methyl]phenyl]-4-[(4-phenylquinazolin-2-yl)amino]benzamide;Benzamide, N-[2-methyl-5-[(methylamino)methyl]phenyl]-4-[(4-phenyl-2-quinazolinyl)amino]-;BMS 833923 N-[2-Methyl-5-[(methylamino)methyl]phenyl]-4-[(4-phenylquinazolin-2-yl)amino]benzamide

Price67 Properties Safety Information Description

67 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
TRC

Package

10mM*1mLinDMSO(Solution)
10mM*1mLinDMSO(Solid+Solvent)
10mM*1mLinDMSO
5mg
10mg
25mg
50mg
100MG
250MG
500mg
1000mg
1g

Manufactureraablocks
Product numberAA008TBU
Product descriptionBMS-833923 98%
Packaging25mg
Price$49
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA008TBU
Product descriptionBMS-833923 98%
Packaging10mg
Price$26
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA008TBU
Product descriptionBMS-833923 98%
Packaging50mg
Price$76
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product number10333
Product descriptionBMS-833923 98%
Packaging100MG
Price$450
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product number10333
Product descriptionBMS-833923 98%
Packaging100MG
Price$450
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10333
Product descriptionBMS-833923 98%
Packaging250MG
Price$900
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product number10333
Product descriptionBMS-833923 98%
Packaging250MG
Price$900
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2281AH
Product descriptionBMS-833923
Packaging10mg
Price$162
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3258
Product descriptionBMS-833923
Packaging50mg
Price$200
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3258
Product descriptionBMS-833923
Packaging50mg
Price$218
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3258
Product descriptionBMS-833923
Packaging5mg
Price$45
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3258
Product descriptionBMS-833923
Packaging10mg
Price$70
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3258
Product descriptionBMS-833923
Packaging10mg
Price$60
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3258
Product descriptionBMS-833923
Packaging5mg
Price$50
Updated2026-05-06
Buy

ManufacturerArctom
Product numberHY-13809
Product descriptionBMS-833923 99.82%
Packaging10mM*1mLinDMSO(Solid+Solvent)
Price$56
Updated2026-05-25
Buy

ManufacturerArctom
Product numberHY-13809
Product descriptionBMS-833923 99.82%
Packaging10mM*1mLinDMSO(Solid+Solvent)
Price$56
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA008TBU	BMS-833923 98%	25mg	$49	2026-05-28	Buy
aablocks	AA008TBU	BMS-833923 98%	10mg	$26	2026-05-28	Buy
aablocks	AA008TBU	BMS-833923 98%	50mg	$76	2026-05-28	Buy
ACHEMBLOCK	10333	BMS-833923 98%	100MG	$450	2026-05-25	Buy
ACHEMBLOCK	10333	BMS-833923 98%	100MG	$450	2026-05-27	Buy
ACHEMBLOCK	10333	BMS-833923 98%	250MG	$900	2026-05-25	Buy
ACHEMBLOCK	10333	BMS-833923 98%	250MG	$900	2026-05-27	Buy
AK Scientific	2281AH	BMS-833923	10mg	$162	2021-12-16	Buy
ApexBio Technology	A3258	BMS-833923	50mg	$200	2021-12-16	Buy
ApexBio Technology	A3258	BMS-833923	50mg	$218	2026-05-06	Buy
ApexBio Technology	A3258	BMS-833923	5mg	$45	2021-12-16	Buy
ApexBio Technology	A3258	BMS-833923	10mg	$70	2021-12-16	Buy
ApexBio Technology	A3258	BMS-833923	10mg	$60	2026-05-06	Buy
ApexBio Technology	A3258	BMS-833923	5mg	$50	2026-05-06	Buy
Arctom	HY-13809	BMS-833923 99.82%	10mM*1mLinDMSO(Solid+Solvent)	$56	2026-05-25	Buy
Arctom	HY-13809	BMS-833923 99.82%	10mM*1mLinDMSO(Solid+Solvent)	$56	2026-05-26	Buy

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Properties

Density :1.252±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥47.4 mg/mL in DMSO; insoluble in H2O; ≥5.14 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :13.42±0.70(Predicted)
color :Light yellow to yellow
InChIKey :KLRRGBHZCJLIEL-UHFFFAOYSA-N
SMILES :C(NC1=CC(CNC)=CC=C1C)(=O)C1=CC=C(NC2=NC(C3=CC=CC=C3)=C3C(=N2)C=CC=C3)C=C1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning		P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.

Description

Smoothened (Smo) is a cell surface receptor that, with Patched, mediates sonic hedgehog (Shh) signaling to regulate gene expression through the Gli transcription factors. BMS 833923 is an orally bioavailable inhibitor of Smo. It blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM). BMS 833923 robustly inhibits Shh pathway activity and prevents tumor growth in medulloblastoma and pancreatic carcinoma xenograft models.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$46.00
BMS-833923 CAS:1059734-66-5

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BMS 833923

Properties

Safety Information

Description

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