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ChemicalBook >> CAS DataBase List >> LY2940680

LY2940680

LY2940680 price.
  • $15 - $5541
  • Product name: LY2940680
  • CAS: 1258861-20-9
  • MF: C26H24F4N6O
  • MW: 512.5
  • EINECS:
  • MDL Number:MFCD21609264
  • Synonyms:Taladegib (LY2940680);4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide LY 2940680;LY2940680;LY2940680 (Taladegib);Taladegib hydrochloride;4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluo;4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide;4-fluoro-N-Methyl-N-(1-(4-(1-Methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoroMethyl)benzaMide
84 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 2.5mg
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100MG
  • 200.00mg
  • 200mg
  • 250mg
  • 1000mg
  • 1.00g
  • 1G
  • Manufactureraablocks
  • Product numberAA000OU8
  • Product descriptionLY2940680 99%(HPLC)
  • Packaging1mg
  • Price$15
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000OU8
  • Product descriptionLY2940680 99%(HPLC)
  • Packaging5mg
  • Price$25
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging5MG
  • Price$45
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging5MG
  • Price$45
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging25MG
  • Price$150
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging25MG
  • Price$150
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging100MG
  • Price$450
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging100MG
  • Price$450
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging1G
  • Price$1450
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8909
  • Product descriptionLY2940680 98%
  • Packaging1G
  • Price$1450
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7613
  • Product description4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide
  • Packaging25mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013718
  • Product description4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00%
  • Packaging5MG
  • Price$498.43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013718
  • Product description4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00%
  • Packaging1MG
  • Price$173.25
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging5mg
  • Price$110
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging50mg
  • Price$470
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000OU8 LY2940680 99%(HPLC) 1mg $15 2026-05-25 Buy
aablocks AA000OU8 LY2940680 99%(HPLC) 5mg $25 2026-05-25 Buy
ACHEMBLOCK H-8909 LY2940680 98% 5MG $45 2026-05-25 Buy
ACHEMBLOCK H-8909 LY2940680 98% 5MG $45 2026-05-27 Buy
ACHEMBLOCK H-8909 LY2940680 98% 25MG $150 2026-05-25 Buy
ACHEMBLOCK H-8909 LY2940680 98% 25MG $150 2026-05-27 Buy
ACHEMBLOCK H-8909 LY2940680 98% 100MG $450 2026-05-25 Buy
ACHEMBLOCK H-8909 LY2940680 98% 100MG $450 2026-05-27 Buy
ACHEMBLOCK H-8909 LY2940680 98% 1G $1450 2026-05-25 Buy
ACHEMBLOCK H-8909 LY2940680 98% 1G $1450 2026-05-27 Buy
AK Scientific X7613 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide 25mg $254 2021-12-16 Buy
American Custom Chemicals Corporation API0013718 4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00% 5MG $498.43 2021-12-16 Buy
American Custom Chemicals Corporation API0013718 4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00% 1MG $173.25 2021-12-16 Buy
ApexBio Technology A8651 LY2940680 5mg $120 2021-12-16 Buy
ApexBio Technology A8651 LY2940680 5mg $110 2026-05-06 Buy
ApexBio Technology A8651 LY2940680 50mg $470 2021-12-16 Buy

Properties

Boiling point :703.5±60.0 °C(Predicted)
Density :1.39
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥5.2 mg/mL in EtOH with ultrasonic; ≥51.3 mg/mL in DMSO with gentle warming and ultrasonic
form :crystalline solid
pka :7.94±0.30(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors. LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro). The potential anticancer activity of LY2940680 is currently under clinical investigation.

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