1,2,3,4-Tetrafluorobenzene synthesis
- Product Name:1,2,3,4-Tetrafluorobenzene
- CAS Number:551-62-2
- Molecular formula:C6H2F4
- Molecular Weight:150.07
1201-31-6
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$10.00/5g
551-62-2
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$10.00/1g
Yield:551-62-2 94.4%
Reaction Conditions:
with ammonia;copper in water at 240; for 1.25 h;Temperature;Reagent/catalyst;
Steps:
15
300 g was added to a 500 mL intermittent high pressure reaction kettleAmmonia concentration of 5g / L aqueous ammonia solution, 50g 2, 3, 4, 5-tetrafluorobenzoic acid and 1.67 g of copper powder, Heating to 240 ° C decarboxylation reaction 1. 25h; decarboxylation reaction is completed, Open the exhaust valve pressure relief, recovery of ammonia inside the kettle; cooling to room temperature, The organic phase and the aqueous phase were obtained by the separation of the filtrate and the filtrate. After the organic phase was distilled 1,2,3,4-tetrafluorobenzene 36. 5 g,was obtained by distillation. The purity of the product by HPLC was 99.1% The yield was 94.4%.
References:
Zhejiang Chemical Industry Institute Technology Co., Ltd;Zhejiang University;Fu, Jie;Mo, Jing;Lyu, Xiuyang;XU, Weiguo CN105732302, 2016, A Location in patent:Paragraph 0047; 0048
652-03-9
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551-62-2
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392-56-3
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372-38-3
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327-54-8
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551-62-2
252 suppliers
$10.00/1g
392-56-3
299 suppliers
$9.00/1g
327-54-8
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$10.00/10g
551-62-2
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$10.00/1g
363-72-4
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367-23-7
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