1-BROMO-2-BUTANOL synthesis
- Product Name:1-BROMO-2-BUTANOL
- CAS Number:2482-57-7
- Molecular formula:C4H9BrO
- Molecular Weight:153.02
558-13-4
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584-03-2
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$8.00/5g
2482-57-7
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$60.00/500mg
Yield: 90%
Reaction Conditions:
with triphenylphosphine in pyridine;ethyl acetate
Steps:
1.B B.
Carbontetrabromide (26.6 g, 80 mmol) and triphenylphosphine (21 g, 80 mmol) were added successively to 1,2-butanediol (7.2 g, 80 mmol) in anhydrous pyridine at 0° C., and the solution stirred at room temperature overnight. The mixture was concentrated and the residual oil dropwise added to vigorously stirred 1:5 ethyl acetate:hexanes (220 mL). The solution was decanted from the precipitate, concentrated, chromatographed (40 g silica gel, 1:3 ethyl acetate:hexanes), and gave GDLZ103 (11.5 g, 90%).
References:
GlycoDesign US6048870, 2000, A
106-88-7
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2482-57-7
47 suppliers
$60.00/500mg
106-98-9
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2482-57-7
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$60.00/500mg
40348-66-1
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$22.00/1g
2482-57-7
47 suppliers
$60.00/500mg
106-88-7
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$15.00/25mL
24068-63-1
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2482-57-7
47 suppliers
$60.00/500mg