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ChemicalBook CAS DataBase List 1-METHOXY-2-BUTANOL
53778-73-7

1-METHOXY-2-BUTANOL synthesis

9synthesis methods
-

Yield: 38% , 58%

Reaction Conditions:

with graphite oxide at 20; for 1 h;

Steps:

General procedure for the alcoholysis of epoxides:
General procedure: To a solution of epoxide(1 mmol) and alcohol (5 mmol) was added 1 mg of graphite oxide (GO) at room temperature and the mixture stirred for the time indicated in Table 2 prior to GC/MS analysis. CH2Cl2 was added and the mixture was filtered and evaporated under reduced pressure. Pure products were isolated by flash column chromatography using hexane/EtOAc (6:1) as eluent.

References:

Mirza-Aghayan, Maryam;Alizadeh, Mahdi;Molaee Tavana, Mahdieh;Boukherroub, Rabah [Tetrahedron Letters,2014,vol. 55,# 49,p. 6694 - 6697]

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