1-methyl-2-phenylbenzimidazole synthesis
- Product Name:1-methyl-2-phenylbenzimidazole
- CAS Number:2622-63-1
- Molecular formula:C14H12N2
- Molecular Weight:208.26
612-28-2
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2835-06-5
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2622-63-1
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$65.00/100mg
Yield: 79%
Reaction Conditions:
with potassium carbonate in toluene at 140; for 24 h;Schlenk technique;Sealed tube;
Steps:
12 Embodiment 12
In a clean dry 10 ml Schlenk reaction tube, sequentially adding a 2-nitro-N-methylaniline 38 mg, benzene glycine 113 mg, potassium carbonate 80 mg, in order to 1 ml of toluene as a solvent, the reaction tube seal, in 140 °C reaction under 24 hours. After the reaction, the reaction mixture directly by rotating the evaporimeter turns on lathe does, then the volume ratio of 8:1 of petroleum ether and ethyl acetate as the eluant, by separating by silica gel column, to obtain 39 mg light yellow solid, yield 79%.
References:
Xinyang Normal University;Tang, Lin;Tan, Meirong CN105777662, 2016, A Location in patent:Paragraph 0090; 0091; 0092
1632-83-3
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591-50-4
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2622-63-1
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$65.00/100mg
4760-34-3
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100-46-9
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2622-63-1
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$65.00/100mg
716-79-0
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74-88-4
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2622-63-1
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$65.00/100mg
1632-83-3
204 suppliers
$6.00/1g
108-86-1
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$10.00/5g
2622-63-1
27 suppliers
$65.00/100mg