1-propylhydrazine hydrochloride synthesis
- Product Name:1-propylhydrazine hydrochloride
- CAS Number:56795-66-5
- Molecular formula:C3H10N2.HCl
- Molecular Weight:111
112383-13-8
56795-66-5
General procedure for the synthesis of n-propylhydrazine hydrochloride from tert-butyl 2-propylhydrazine-1-carboxylate: To a three-necked round-bottomed flask equipped with a stirrer was added 17.4 grams of BOC-propylhydrazine and 90 ml of a dichloromethane solution of 2M hydrochloric acid. The reaction was stirred at room temperature for 4 hours to ensure complete reaction. Upon completion of the reaction, the solvent was removed by reduced pressure distillation and the crude product obtained was pulped with 40 ml of dichloromethane. The solvent was again removed by distillation under reduced pressure, resulting in 9.4 g of white solid product. The product was analyzed by liquid chromatography (LC) with a purity of more than 98% and a yield of 85%.
112383-13-8
4 suppliers
inquiry
56795-66-5
69 suppliers
inquiry
Yield: 85%
Reaction Conditions:
with hydrogenchloride in dichloromethane at 20; for 4 h;
Steps:
6 Embodiment 6: is propyl jing hydrochloride synthetic:
With the stirrer in three-opening reaction bottle is added BOC propyl jing 17.4 g and 2M hydrochloric acid dichloromethane solution 90 ml, room temperature stirring 4h to the reaction is complete,, the decompression, the resulting crude product dichloromethane is used for 40 ml of beating, the decompression to obtain white solid 9.4 g, LC purity 98% or more, the yield is 85%.
References:
Suzhou Hande Chuanghong Biochemical Technology Co., Ltd.;Mao Zhongping;Ma Dongxu;Ge Yonghui;Wei Hua;Tan Jin CN106565531, 2017, A Location in patent:Paragraph 0038; 0047; 0048
561067-08-1
0 suppliers
inquiry
56795-66-5
69 suppliers
inquiry