1-PROPYL-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-3-CARBOXYLIC ACID synthesis
- Product Name:1-PROPYL-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-3-CARBOXYLIC ACID
- CAS Number:147796-05-2
- Molecular formula:C15H18N2O2
- Molecular Weight:258.32
123-72-8
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73-22-3
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147796-05-2
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Yield: 58%
Reaction Conditions:
with sulfuric acid in ethanol;water at 20; for 24 h;
Steps:
I; 18; II Synthesis of 1-propyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (13a)
L- tryptophan (5.10g, 25mmol), water (300ml), H2SO4 (0.5M, 50 ml), n-butyraldehyde (10ml) and ethanol (100ml) were added in a 250 ml round-bottom flask, and then stirred and reacted at room temperature for 24 h. After filtration, wash with water and drying, white solids (3.75g, 58%)were obtained.
References:
Xinjiang Huashidan Pharmaceutical Research Co., Ltd. EP1634881, 2006, A1 Location in patent:Page/Page column 14; 16; 95
123-72-8
447 suppliers
$12.32/25ML
54-12-6
386 suppliers
$6.00/5g
147796-05-2
14 suppliers
$378.00/1g