[R-(E)]-alpha-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol synthesis
- Product Name:[R-(E)]-alpha-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol
- CAS Number:150026-75-8
- Molecular formula:C29H28ClNO2
- Molecular Weight:457.99
88-67-5
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$5.00/5g
150026-75-8
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$110.00/10mg
![2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol](/CAS2/GIF/287930-77-2.gif)
287930-77-2
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Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: sulfuric acid / 24 h / Reflux
2.1: magnesium / diethyl ether / 1.5 h / 20 °C / Inert atmosphere
2.2: 1.25 h / 0 °C / Reflux
3.1: lithium acetate; tetrabutyl-ammonium chloride; lithium chloride / N,N-dimethyl acetamide / 30 h / 20 - 120 °C / Inert atmosphere
4.1: potassium tert-butylate; [((S)-PhanePhos)-((R,R)-DACH)RuCl2]; hydrogen / tetrahydrofuran; isopropyl alcohol / 4 h / 25 °C / 4425.44 - 6000.6 Torr
References:
Bollikonda, Satyanarayana;Mohanarangam, Saravanan;Jinna, Rajender Reddy;Kandirelli, Venkata Kiran Kumar;Makthala, Laxman;Sen, Saikat;Chaplin, David A.;Lloyd, Richard C.;Mahoney, Thomas;Dahanukar, Vilas Hareshwar;Oruganti, Srinivas;Fox, Martin E. [Journal of Organic Chemistry,2015,vol. 80,# 8,p. 3891 - 3901]
676-58-4
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$15.00/25ml
![2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]benzoic Acid Methyl Ester](/CAS2/GIF/150026-72-5.gif)
150026-72-5
35 suppliers
$165.00/25mg
150026-75-8
65 suppliers
$110.00/10mg
88-65-3
375 suppliers
$5.00/5g
150026-75-8
65 suppliers
$110.00/10mg
287930-77-2
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610-94-6
313 suppliers
$13.00/25g
150026-75-8
65 suppliers
$110.00/10mg
287930-77-2
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610-97-9
432 suppliers
$9.00/1g
150026-75-8
65 suppliers
$110.00/10mg
287930-77-2
66 suppliers
inquiry